ArticleInternational journal of nanomedicine2019
Anticancer and antibacterial effects of a clove bud essential oil-based nanoscale emulsion system.
Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The trial behind it
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Who cites it
25 citing papers in PubMed.
- Antitumor Activity of the Ethanolic Extract fromPharmaceutics · 2026Article
- Chemical Characterization, Sensory Evaluation, and Biological Activity in Neuronal Cells of Essential Oils (Rose, Eucalyptus, Lemon, and Clove) Used for Olfactory Training.Molecules (Basel, Switzerland) · 2025Article
- Anticancer Potential ofPlants (Basel, Switzerland) · 2025Article
- Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Comparative antibacterial activity of clove extract against Pseudomonas aeruginosa.BMC complementary medicine and therapies · 2025Article
- Review
- The Incorporation of Clove Essential Oil into Nanostructured Lipid Carrier for Improvement of the Delivery and Antioxidant Effects on the Fibroblast Cells.Pharmaceutical nanotechnology · 2025Article
- In Vitro and In Silico Evaluation ofPlants (Basel, Switzerland) · 2024Article
- Clove Essential Oil: Chemical Profile, Biological Activities, Encapsulation Strategies, and Food Applications.Antioxidants (Basel, Switzerland) · 2024Review
- Natural products' antiangiogenic roles in gynecological cancer.Frontiers in pharmacology · 2024Review
- Development of Phytochemical Delivery Systems by Nano-Suspension and Nano-Emulsion Techniques.International journal of molecular sciences · 2023Review
- Multi-Targeting Neuroprotective Effects ofInternational journal of molecular sciences · 2023Article
- Anticancer Applications of Essential Oils Formulated into Lipid-Based Delivery Nanosystems.Pharmaceutics · 2022Review
- Review
- Article
- Exploration of Clove Bud (Insects · 2022Article
- Essential Oils and Neuropathic Pain.Plants (Basel, Switzerland) · 2022Review
- Traditional uses, pharmacological activities, and phytochemical constituents of the genusFood science & nutrition · 2022Review
- In Vitro Assessment of the Cytotoxic and Antiproliferative Profile of Natural Preparations Containing Bergamot, Orange and Clove Essential Oils.Molecules (Basel, Switzerland) · 2022Article
- The nanocomposites designs of phytomolecules from medicinal and aromatic plants: promising anticancer-antiviral applications.Beni-Suef University journal of basic and applied sciences · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe essential oil derived from clove buds (
methodsNanoscale-based emulsions were prepared by employing a spontaneous emulsification technique through self-assembly using varying concentrations of Tween 20 and Tween 80 surfactants. Their physicochemical properties and stability were studied in order to choose an optimum formulation which was clear and stable. The cytotoxicity of the stable oil-based emulsion system was evaluated using MTT assay, colony formation assay, and Annexin V-FITC assay against the thyroid cancer cell line (HTh-7).
resultsAll three methods verified apoptosis and reduction in cancer cell proliferation, making the formulation a promising candidate as an alternative cancer drug. The oil-based emulsion system was also tested for its antibacterial properties against
conclusionMany current treatments for cancers are aggressive yet ineffective. This study positions the clove bud-based nanoscale emulsion as a suitable candidate for further in vivo studies and trials as a cancer drug.
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Registered trials
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