Evidence map›Paper›PMID 31496682›Full record

ArticleInternational journal of nanomedicine2019

Antiviral potential of green synthesized silver nanoparticles of

Eman G Haggag, Ali M Elshamy, Mohamed A Rabeh, Nagwan M Gabr, Mohamed Salem, Khayrya A Youssif, Ahmed Samir, Abdullatif Bin Muhsinah, Abdulrhman Alsayari, Usama Ramadan Abdelmohsen

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

  1. Gellan Gum/Alginate Films Containing BiogenicMolecules (Basel, Switzerland) · 2026
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  11. Article
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  13. Prospects ofHeliyon · 2024
    Article
  14. Antimicrobial Activity ofInternational journal of molecular sciences · 2024
    Article
  15. Article
  16. Biosynthesis and Characterization ofInternational journal of molecular sciences · 2024
    Article
  17. Article
  18. Review
  19. Review
  20. Review

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eman G HaggagDepartment of Pharmacognosy, Faculty of Pharmacy, Helwan University, Cairo 11795, Egypt.
Ali M ElshamyDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Mohamed A RabehDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Nagwan M GabrDepartment of Pharmacognosy, Faculty of Pharmacy, Helwan University, Cairo 11795, Egypt.
Mohamed SalemDepartment of Pharmaceutical Chemistry, October University for Modern Sciences and Arts (Msa), Cairo, Egypt.
Khayrya A YoussifDepartment of Pharmacognosy, Faculty of Pharmacy, Modern University for Technology and Information, Cairo, Egypt.
Ahmed SamirDepartment of Pharmaceutical Chemistry, October University for Modern Sciences and Arts (Msa), Cairo, Egypt.
Abdullatif Bin MuhsinahDepartment of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia.
Abdulrhman AlsayariDepartment of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia.
Usama Ramadan AbdelmohsenDepartment of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundViral and microbial infections constitute one of the most important life-threatening problems. The emergence of new viral and bacterial infectious diseases increases the demand for new therapeutic drugs. PURPOSE: The objective of this study was to use the aqueous and hexane extracts of

methodsThe formation of SNPs was further confirmed using a transmission electron microscope (TEM), UV-Visible spectroscopy and Fourier transform infrared spectroscopy. The antiviral activity of the synthesized nanoparticles was evaluated using MTT assay against HSV-1, HAV-10 virus and Coxsackie B4 virus. Metabolomics profiling was performed using UPLC-MS and molecular docking was performed via Autodock4 and visualization was done using the Discovery studio.

resultsThe early signs of SNPs synthesis were detected by a color change from yellow to reddish brown color. The TEM analysis of SNPs showed spherical nanoparticles with mean size ranges between 10.12 nm to 27.89 nm, and 8.91 nm 14.48 nm for

conclusionThese results highlight that SNPs of

Indexed as

Green Chemistry TechnologyAizoaceaeAnimalsAntiviral AgentsCell DeathChlorocebus aethiopsLigandsMetabolomicsMetal NanoparticlesMolecular Docking SimulationPlant ExtractsSilverSpectrophotometry, UltravioletSpectroscopy, Fourier Transform InfraredVero CellsAntiviral AgentsLigandsPlant ExtractsSilverantiviralLampranthus coccineusMalephora luteametabolomics profilingsilver nanoparticles

Identifiers

PMID31496682
PMCPMC6690046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.