Evidence map›Paper›PMID 31496681›Full record

ArticleInternational journal of nanomedicine2019

Mechano-signalling, induced by fullerene C

Malwina Sosnowska, Marta Kutwin, Sławomir Jaworski, Barbara Strojny, Mateusz Wierzbicki, Jarosław Szczepaniak, Maciej Łojkowski, Wojciech Święszkowski, Jaśmina Bałaban, André Chwalibog and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. Fullerene CInternational journal of molecular sciences · 2024
    Article
  2. Article
  3. Review
  4. Polyhydroxylated Fullerene CJournal of inflammation research · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Malwina SosnowskaDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
Marta KutwinDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
Sławomir JaworskiDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
Barbara StrojnyDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
Mateusz WierzbickiDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
Jarosław SzczepaniakDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
Maciej ŁojkowskiFaculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw 00-661, Poland.
Wojciech ŚwięszkowskiFaculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw 00-661, Poland.
Jaśmina BałabanDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
André ChwalibogDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
Ewa SawoszDepartment of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw 02-786, Poland.
Warsaw University of Life Sciences · PLWarsaw University of Technology · PLUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectiveDegradation of the extracellular matrix (ECM) changes the physicochemical properties and dysregulates ECM-cell interactions, leading to several pathological conditions, such as invasive cancer. Carbon nanofilm, as a biocompatible and easy to functionalize material, could be used to mimic ECM structures, changing cancer cell behavior to perform like normal cells.

methodsExperiments were performed in vitro with HS-5 cells (as a control) and HepG2 and C3A cancer cells. An aqueous solution of fullerene C

resultsAll cell lines were spread on C

conclusionThe results indicate that C

Indexed as

Mechanotransduction, CellularCell CommunicationCell Cycle CheckpointsCell DivisionCell Line, TumorCell ProliferationCell ShapeCell SurvivalCytoskeletonElastic ModulusExtracellular MatrixFullerenesG2 PhaseHumansIntegrin alpha5beta1Liver NeoplasmsFullerenesIntegrin alpha5beta1Neoplasm Proteinsadhesioncell cycleextracellular matrixfullereneliver cancer cells

Identifiers

PMID31496681
PMCPMC6689765
OpenAlexW2964354578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.