ArticleWorld journal of gastroenterology2019
Application of indocyanine green-enhanced near-infrared fluorescence-guided imaging in laparoscopic lateral pelvic lymph node dissection for middle-low rectal cancer.
Article in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04173676 (Sentinel Lymph Node Navigation Using Near-infrared Imaging in Radical Esophagectomy Surgery ：a Single-arm Clinical Trial), which is not on this map. Cited by 40 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sentinel Lymph Node Navigation Using Near-infrared Imaging in Radical Esophagectomy Surgery ：a Single-arm Clinical Trial
Who cites it
40 citing papers in PubMed, 7 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- SAGES 2025 guidelines for fluorescence image-guided gastrointestinal surgery using indocyanine green.Surgical endoscopy · 2025Guideline
- SAGES 2025 systematic review and meta-analysis for fluorescence image-guided gastrointestinal surgery using indocyanine green.Surgical endoscopy · 2025Pooled it
- The use of indocyanine green for colorectal anastomoses: a systematic review and meta-analysis.Annals of the Royal College of Surgeons of England · 2025Pooled it
- The use of indocyanine green for lateral lymph node dissection in rectal cancer-preliminary data from an emerging procedure: a systematic review of the literature.Techniques in coloproctology · 2024Pooled it
- Indocyanine green fluorescence angiography decreases the risk of anastomotic leakage after rectal cancer surgery: a systematic review and meta-analysis.Frontiers in medicine · 2023Pooled it
- Meta analysis of indocyanine green fluorescence in patients undergoing laparoscopic colorectal cancer surgery.Frontiers in oncology · 2022Pooled it
- Assessment of intraoperative use of indocyanine green fluorescence imaging on the incidence of anastomotic leakage after rectal cancer surgery: a PRISMA-compliant systematic review and meta-analysis.Techniques in coloproctology · 2021Pooled it
- Feasibility of using artificial intelligence models to identify the obturator nerve in laparoscopic selective lateral pelvic lymph node dissection.Surgical endoscopy · 2026Article
- Real-time indocyanine green fluorescence imaging enhances the precision of lymph node dissection in laparoscopic colon cancer surgery: a propensity score-matched cohort study.Surgical endoscopy · 2026Article
- Fluorescence-Guided Surgery in Colorectal Cancer: State-of-the-Art and Translational Perspectives.Current oncology (Toronto, Ont.) · 2026Review
- Fluorescence-guided surgery in colorectal cancer: current evidence, quantitative advances, and future perspectives.Annals of coloproctology · 2026Review
- Review
- Surgical navigation for lateral pelvic lymph node dissection in rectal cancer.Techniques in coloproctology · 2025Review
- Management of internal iliac and obturator lymph nodes in mid-low rectal cancer.World journal of surgical oncology · 2024Review
- Indocyanine green near-infrared fluorescence-assisted video endoscopic inguinal lymph node dissection for rectal cancer: a single-center experience.Techniques in coloproctology · 2024Article
- Fluorescence-guided colorectal surgery: applications, clinical results, and protocols.Annals of surgical treatment and research · 2023Review
- Indocyanine green dye and its application in gastrointestinal surgery: The future is bright green.World journal of gastrointestinal surgery · 2023Review
- Long-term outcomes of indocyanine green fluorescence imaging-guided laparoscopic lateral pelvic lymph node dissection for clinical stage II/III middle-lower rectal cancer: a propensity score-matched cohort study.Techniques in coloproctology · 2023Article
- Lateral pelvic sentinel lymph node biopsy using indocyanine green fluorescence navigation: can it be a powerful supplement tool for predicting the status of lateral pelvic lymph nodes in advanced lower rectal cancer.Surgical endoscopy · 2023Article
- Intraoperative near-infrared lymphography with indocyanine green may aid lymph node dissection during robot-assisted resection of gastroesophageal junction cancer.Surgical endoscopy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs one effective treatment for lateral pelvic lymph node (LPLN) metastasis (LPNM), laparoscopic LPLN dissection (LPND) is limited due to the complicated anatomy of the pelvic sidewall and various complications after surgery. With regard to improving the accuracy and completeness of LPND as well as safety, we tried an innovative method using indocyanine green (ICG) visualized with a near-infrared (NIR) camera system to guide the detection of LPLNs in patients with middle-low rectal cancer.
aimTo investigate whether ICG-enhanced NIR fluorescence-guided imaging is a better technique for LPND in patients with rectal cancer.
methodsA total of 42 middle-low rectal cancer patients with clinical LPNM who underwent total mesorectal excision (TME) and LPND between October 2017 and March 2019 at our institution were assessed and divided into an ICG group and a non-ICG group. Clinical characteristics, operative outcomes, pathological outcomes, and postoperative complication information were compared and analysed between the two groups.
resultsCompared to the non-ICG group, the ICG group had significantly lower intraoperative blood loss (55.8 ± 37.5 mL
conclusionICG-enhanced NIR fluorescence-guided imaging could be a feasible and convenient technique to guide LPND because it could bring specific advantages regarding the accuracy and completeness of surgery as well as safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.