ReviewWorld journal of gastroenterology2019
Lateral lymph node dissection for low rectal cancer: Is it necessary?
Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Robotic versus laparoscopic total mesorectal excision for mid-low rectal cancer after neoadjuvant chemoradiotherapy: a systematic review and meta-analysis of oncological, perioperative, and survival-related outcomes.Journal of robotic surgery · 2025Pooled it
- Rise and fall of total mesorectal excision with lateral pelvic lymphadenectomy for rectal cancer: an updated systematic review and meta-analysis of 11,366 patients.International journal of colorectal disease · 2021Pooled it
- Article
- Effect of methylene blue infusion into the inferior mesenteric artery on lymph node retrieval after transabdominal total mesorectal excision for rectal cancer: a retrospective cohort study.Frontiers in oncology · 2026Article
- Radiotherapy volume delineation based on MRI andAbdominal radiology (New York) · 2025Article
- MRI-based scoring systems for selective lateral lymph node dissection in locally advanced low rectal cancer after neoadjuvant chemoradiotherapy.European radiology · 2025Article
- Predicting lateral pelvic lymph node metastasis in rectal cancer patients using MRI radiomics: a multicenter retrospective study.Scientific reports · 2025Article
- Clinical and pathological features of advanced rectal cancer with submesenteric root lymph node metastasis: Meta-analysis.World journal of gastrointestinal oncology · 2024Article
- Late Local Recurrence after Neoadjuvant Therapy and Radical Resection for Locally Advanced Rectal Cancer.Cancers · 2024Article
- Enlarged tumour-draining lymph node with immune-activated profile predict favourable survival in non-metastatic colorectal cancer.British journal of cancer · 2024Article
- Significant improvement after training in the assessment of lateral compartments and short-axis measurements of lateral lymph nodes in rectal cancer.European radiology · 2023Article
- Total Mesorectal Excision with or without Lateral Pelvic Lymph Node Dissection in Rectal Cancer.International journal of surgical oncology · 2023Article
- Retrospective evaluation of national MRI reporting quality for lateral lymph nodes in rectal cancer patients and concordance with prospective re-evaluation following additional training.Insights into imaging · 2022Article
- Extended Lymphadenectomy in Locally Advanced Rectal Cancers: A Systematic Review.Annals of coloproctology · 2022Article
- Clinical implication and management of rectal cancer with clinically suspicious lateral pelvic lymph node metastasis: A radiation oncologist's perspective.Frontiers in oncology · 2022Review
- From "East vs West" towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer.Annals of gastroenterological surgery · 2021Review
- Radiomics and machine learning applications in rectal cancer: Current update and future perspectives.World journal of gastroenterology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rectal cancer constitutes a major public health issue. Total mesorectal excision has remained the gold standard treatment for mid and low rectal tumors since its introduction in the late 1980s. Removal of all lymph nodes located in the mesorectum has indeed improved pathological and oncological outcomes. However, when cancer spreads to the lateral lymph nodes (located along the iliac and obturator arteries) Western and Japanese practices differ. Where the Western guidelines consider this condition as an advanced form of the disease and use neoadjuvant radiochemotherapy liberally, the Japanese guidelines define it as a local disease and proceed to lateral lymph node dissection with or without neoadjuvant treatment. Herein, we review the current literature regarding both therapeutic strategies, with the aim of contributing to potential improvements in treatment and outcome for patients with low and mid rectal cancer.
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Registered trials
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