Evidence map›Paper›PMID 31496537›Full record

Trial reportMedical science monitor : international medical journal of experimental and clinical research2019

Effect of High-Intensity Focused Ultrasound Versus Plasma Radiofrequency Ablation on Recurrent Allergic Rhinitis.

Bing Zhong, Lin-Ke Li, Di Deng, Jin-Tao Du, Ya-Feng Liu, Feng Liu, Shi-Xi Liu

Registry-linked trialOpen access · hybridAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medical science monitor : international medical journal of experimental and clinical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06272032 (Prospective Multicenter Observational Study and Promotion of the Application of Focused Ultrasound in "Reduction of Hypertrophy" and "Desensitization" for Allergic Rhinitis), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06272032 early_phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Prospective Multicenter Observational Study and Promotion of the Application of Focused Ultrasound in "Reduction of Hypertrophy" and "Desensitization" for Allergic Rhinitis

TypeinterventionalSponsorChongqing Medical UniversityRan2023 to 2025Enrolled240ConditionsAllergic RhinitisArmsHigh-intensity focused ultrasound (HIFU), intranasal corticosteroids, oral antihistamines, oral leukotriene receptor antagonists, and intranasal antihistamines
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Medical devices in allergy practice.The World Allergy Organization journal · 2020
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bing ZhongDepartment of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).
Lin-Ke LiDepartment of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).
Di DengDepartment of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).
Jin-Tao DuDepartment of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).
Ya-Feng LiuDepartment of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).
Feng LiuDepartment of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).
Shi-Xi LiuDepartment of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND High-intensity focused ultrasound (HIFU) and plasma radiofrequency ablation (PRA) have been used to treat recurrent allergic rhinitis (AR); however, there is a lack of literature comparing the efficacy of these 2 methods. We assessed and compared the therapeutic effects of HIFU and PRA on recurrent AR. MATERIAL AND METHODS We enrolled 66 patients with recurrent AR at West China Hospital of Sichuan University. Visual analogue score (VAS), pain score, rhinoconjunctivitis quality of life questionnaire (RQLQ), and nasal endoscopy were performed to evaluate the therapeutic effect. RESULTS Nasal endoscopy showed that HIFU and PAR reduced the volume of the inferior turbinate, whereas HIFU reduced the amount of nasal secretions in patients. VAS scores showed that HIFU and PRA nasal congestion symptoms were significantly reduced (P<0.05). The preoperative VAS scores for nasal fluid and sneezing were significantly lower in patients receiving HIFU (P<0.05) than in those receiving PRA (P>0.05). HIFU-treated patients had significantly lower postoperative pain scores than those in the PRA group (P<0.05). RQLQ showed activity, sleep, and non-nasal or ocular symptoms, and both HIFU and PRA patients had significantly lower scores (P<0.05). Nasal symptom scores, actual problems, and mood in the HIFU group were significantly worse than those in the PRA group (P<0.05). However, neither treatment had a significant effect on ocular symptoms (P>0.05). CONCLUSIONS Compared with PRA, HIFU can significantly reduce the nasal symptoms of AR patients, improve the quality of life, and can be used as an adjuvant therapy with better therapeutic effect.

Indexed as

Catheter AblationHigh-Intensity Focused Ultrasound AblationAdultEndoscopyFemaleHumansMaleRecurrenceRhinitis, AllergicVisual Analog Scale

Identifiers

PMID31496537
PMCPMC6752098
OpenAlexW2973215515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.