Evidence map›Paper›PMID 31496451›Full record

ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2019

Children of the Twins Early Development Study (CoTEDS): A Children-of-Twins Study.

Yasmin I Ahmadzadeh, Thalia C Eley, Robert Plomin, Philip S Dale, Kathryn J Lester, Bonamy R Oliver, Andrew McMillan, Tom A McAdams

Abstract readTwin Study
In one paragraph

Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Review
  2. Article
  3. Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development from Infancy to Emerging Adulthood.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yasmin I AhmadzadehSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Thalia C EleySocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Robert PlominSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Philip S DaleDepartment of Speech and Hearing Sciences, University of New Mexico, Albuquerque, NM, USA.
Kathryn J LesterSchool of Psychology, University of Sussex, Brighton, UK.
Bonamy R OliverDepartment of Psychology, Goldsmiths, University of London, London, UK.
Andrew McMillanSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Tom A McAdamsSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Funding

Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife2)R01AG046938 · NIA · UNIVERSITY OF COLORADO · PI REYNOLDS, CHANDRA A, WADSWORTH, SALLY J · 2015 to 2024
$18.5M
Genetics, School environments and cognitive developmentR01HD044454 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2005 to 2014
$3.4M
Genetics of Mathematical Cognition and DisabilitiesR01HD059215 · NICHD · OHIO STATE UNIVERSITY · PI PETRILL, STEPHEN A. · 2009 to 2012
$2.4M
Department of HealthMedical Research Council G0901245Medical Research Council G19/2Medical Research Council MR/M021475/1NIA NIH HHS R01 AG046938NICHD NIH HHS R01 HD044454NICHD NIH HHS R01 HD059215Wellcome TrustWellcome Trust 107706/Z/15/Z
6 · The paper itself

Abstract

The Children of the Twins Early Development Study (CoTEDS) is a new prospective children-of-twins study in the UK, designed to investigate intergenerational associations across child developmental stages. CoTEDS will enable research on genetic and environmental factors that underpin parent-child associations, with a focus on mental health and cognitive-related traits. Through CoTEDS, we will have a new lens to examine the roles that parents play in influencing child development, as well as the genetic and environmental factors that shape parenting behavior and experiences. Recruitment is ongoing from the sample of approximately 20,000 contactable adult twins who have been enrolled in the Twins Early Development Study (TEDS) since infancy. TEDS twins are invited to register all offspring to CoTEDS at birth, with 554 children registered as of May 2019. By recruiting the second generation of TEDS participants, CoTEDS will include information on adult twins and their offspring from infancy. Parent questionnaire-based data collection is now underway for 1- and 2-year-old CoTEDS infants, with further waves of data collection planned. Current data collection includes the following primary constructs: child mental health, temperament, language and cognitive development; parent mental health and social relationships; parenting behaviors and feelings; and other socioecological factors. Measurement tools have been selected with reference to existing genetically informative cohort studies to ensure overlap in phenotypes measured at corresponding stages of development. This built-in study overlap is intended to enable replication and triangulation of future analyses across samples and research designs. Here, we summarize study protocols and measurement procedures and describe future plans.

Indexed as

Child DevelopmentAdolescentAdultChildChild Behavior DisordersChild of Impaired ParentsChild, PreschoolDiseases in TwinsFemaleHumansIncidenceInfantInfant, NewbornLongitudinal StudiesMaleMental HealthBehavioral geneticschildren-of-twinsfamilieslongitudinaloffspringparents

Identifiers

PMID31496451
PMCPMC7056591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.