Evidence map›Paper›PMID 31496448›Full record

SynthesisEpidemiology and infection2019

Do we know how scabies outbreaks in residential and nursing care homes for the elderly should be managed? A systematic review of interventions using a novel approach to assess evidence quality.

E J Morrison, J Middleton, S Lanza, J E Cowen, K Hewitt, S L Walker, M Nicholls, J Rajan-Iyer, J Fletcher, J A Cassell

Abstract readSystematic Review
In one paragraph

Synthesis in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  9. Article
  10. Pathogens (Basel, Switzerland) · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

E J MorrisonBrighton and Sussex Medical School, Brighton, UK.ORCID 0000-0003-2772-5960
J MiddletonBrighton and Sussex Medical School, Brighton, UK.ORCID 0000-0001-5951-6608
S LanzaBrighton and Sussex Medical School, Brighton, UK.
J E CowenBrighton and Sussex Medical School, Brighton, UK.
K HewittSurrey and Sussex HPT (South East), Public Health England, County Hall North, Chart Way, Horsham, West Sussex RH12 1XA, UK.
S L WalkerFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
M NichollsSurrey and Sussex HPT (South East), Public Health England, County Hall North, Chart Way, Horsham, West Sussex RH12 1XA, UK.
J Rajan-IyerSurrey and Sussex HPT (South East), Public Health England, County Hall North, Chart Way, Horsham, West Sussex RH12 1XA, UK.
J FletcherBrighton and Sussex Medical School, Brighton, UK.
J A CassellBrighton and Sussex Medical School, Brighton, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently no national guidelines exist for the management of scabies outbreaks in residential or nursing care homes for the elderly in the United Kingdom. In this setting, diagnosis and treatment of scabies outbreaks is often delayed and optimal drug treatment, environmental control measures and even outcome measures are unclear. We undertook a systematic review to establish the efficacy of outbreak management interventions and determine evidence-based recommendations. Four electronic databases were searched for relevant studies, which were assessed using a quality assessment tool drawing on STROBE guidelines to describe the quality of observational data. Nineteen outbreak reports were identified, describing both drug treatment and environmental management measures. The quality of data was poor; none reported all outcome measures and only four described symptom relief measures. We were unable to make definitive evidence-based recommendations. We draw on the results to propose a framework for data collection in future observational studies of scabies outbreaks. While high-quality randomised controlled trials are needed to determine optimal drug treatment, evidence on environmental measures will need augmentation through other literature studies. The quality assessment tool designed is a useful resource for reporting of outcome measures including patient-reported measures in future outbreaks.

Indexed as

AgedCommunity-Acquired InfectionsCross InfectionDisease OutbreaksDisease Transmission, InfectiousHumansInfection ControlNursing HomesScabiesUnited KingdomElderly medicineinfectious disease controloutbreaksresidential carescabies

Identifiers

PMID31496448
PMCPMC6805746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.