Evidence map›Paper›PMID 31496160›Full record

Trial reportZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2019

[Effect of trimetazidine on cardiac function and exercise tolerance in hypertension patients with diabetic].

Pingxian Ye, Pingzhen Ye, Jinping He

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pingxian YeDepartment of Cardiology, Zhejiang Jinhua Guangfu Hospital, Jinhua 321000, Zhejiang Province, China.
Pingzhen YeDepartment of Cardiology, Zhejiang Jinhua Guangfu Hospital, Jinhua 321000, Zhejiang Province, China.
Jinping HeDepartment of Cardiology, Zhejiang Jinhua Guangfu Hospital, Jinhua 321000, Zhejiang Province, China.
Guang Fu Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the effect of trimetazidine on cardiac function and exercise tolerance in primary hypertension patients with type 2 diabetic.

methodsIn this randomized, double-blind, placebo-controlled prospective study, 60 primary hypertensive patients with diabetic were equally assigned into two groups, patients received trimetazidine (20 mg, 3 times a day) or placebo for 1 year. Echocardiography, cardiopulmonary exercise testing were performed; and the plasma N terminal pro B type natriuretic peptide (NT-ProBNP), hr-CRP, TNF-α, angiotensin Ⅱ and endothelin concentration were determined before and after treatment.

resultsIn trimetazidine group, the left ventricular mass index, the mitral flow velocity E wave to A wave ratio (E/A), the peak early diastolic velocity (V

conclusionsFor patients with both hypertension and diabetes, trimetazidine can improve cardiac function and increase exercise tolerance.

Indexed as

Diabetes ComplicationsDiabetes MellitusExercise ToleranceHeartHypertensionTrimetazidineDouble-Blind MethodHumansNatriuretic Peptide, BrainProspective StudiesTreatment OutcomeVasodilator AgentsNatriuretic Peptide, BrainTrimetazidineVasodilator Agents

Identifiers

PMID31496160
PMCPMC8800787
OpenAlexW2973975459

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.