ArticlePediatric pulmonology2019
Bacterial salivary microbiome associates with asthma among african american children and young adults.
Article in Pediatric pulmonology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed.
- Article
- Microbiome and metabolome integrated analysis reveals oral microbiota alterations and associated metabolic pathways in allergic rhinitis.Journal of oral microbiology · 2026Article
- Oral microbiota and respiratory diseases: advances and perspectives.Clinical microbiology reviews · 2025Review
- The Role of Biodiversity in the Development of Asthma and Allergic Sensitization: A State-of-the-Science Review.Environmental health perspectives · 2024Review
- The salivary microbiota of patients with acute lower respiratory tract infection-A multicenter cohort study.PloS one · 2024Article
- The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?Journal of clinical medicine · 2023Review
- Characteristics of the oropharyngeal microbiota among infants with pneumonia and their effects on immune response and subsequent respiratory morbidity.European journal of pediatrics · 2023Article
- Bacterial Microbiota of Asthmatic Children and Preschool Wheezers' Airways-What Do We Know?Microorganisms · 2023Review
- Paediatric Asthma and the Microbiome: A Systematic Review.Microorganisms · 2023Review
- Characterization of the salivary microbiome before and after antibiotic therapy via separation technique.Applied microbiology and biotechnology · 2023Article
- Nasal Bacteriomes of Patients with Asthma and Allergic Rhinitis Show Unique Composition, Structure, Function and Interactions.Microorganisms · 2023Article
- Characterization of the upper respiratory tract microbiota in Chilean asthmatic children reveals compositional, functional, and structural differences.Frontiers in allergy · 2023Article
- Immunomodulatory role of oral microbiota in inflammatory diseases and allergic conditions.Frontiers in allergy · 2023Review
- The oral bacteriomes of patients with allergic rhinitis and asthma differ from that of healthy controls.Frontiers in microbiology · 2023Article
- Lung microbiome alterations in patients with anti-Jo1 antisynthetase syndrome and interstitial lung disease.Frontiers in cellular and infection microbiology · 2023Article
- Bronchoalveolar Lavage Fluid-Isolated Biomarkers for the Diagnostic and Prognostic Assessment of Lung Cancer.Diagnostics (Basel, Switzerland) · 2022Review
- Future Prospect of Oral Microbiota Influencing Allergy/Asthma Development.Frontiers in microbiology · 2022Article
- Relationship of the lung microbiome with PD-L1 expression and immunotherapy response in lung cancer.Respiratory research · 2021Article
- Respiratory and Neurological Disease across Different Ethnic Groups Is Influenced by the Microbiome.Microorganisms · 2021Review
- A narrative review of exploring potential salivary biomarkers in respiratory diseases: still on its way.Journal of thoracic disease · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Several studies have shown that the airways of asthma patients contain higher diversity of bacteria and are enriched in pathogenic species. However, sampling the airways in children is challenging. Here we aimed to identify differences in the salivary bacterial composition between African Americans children with and without asthma. Saliva samples from 57 asthma cases and 57 healthy controls were analyzed by means of 16S ribosomal RNA amplicon profiling. Measurements of bacterial diversity and genus relative abundance were compared between cases and controls using the nonparametric Wilcoxon test and multivariate regression models. A total of five phyla and a mean of 56 genera were identified. Among them, 15 genera had a relative abundance greater than 1%, being Prevotella, Haemophilus, Streptococcus, and Veillonella the most abundant genera. Differences between cases and controls were found in terms of diversity, as well as in relative abundance for Streptococcus genus (13.0% in cases vs 18.3% in controls; P = .003) and Veillonella genus (11.1% in cases vs 8.0% in controls; P = .002). These differences remained significant after correction for multiple comparisons and when potential confounders were taken into account in logistic regression models. In conclusion, we identified changes in the salivary microbiota associated with asthma among African Americans.
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