Evidence map›Paper›PMID 31495475›Full record

ArticleSpine deformity2019

Bone Remodeling and Disc Morphology in the Distal Unfused Spine After Spinal Fusion in Adolescent Idiopathic Scoliosis.

Saba Pasha, Lachlan Smith, Wudbhav N Sankar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Spine deformity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Surgical outcome differences between the 3D subtypes of right thoracic adolescent idiopathic scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Saba PashaDivision of Orthopaedic Surgery, Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: pashas@email.chop.edu.
Lachlan SmithDepartments of Neurosurgery and Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
Wudbhav N SankarDivision of Orthopaedic Surgery, Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
University of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

Pathogenesis and Treatment of Bone Disease in the MucopolysaccharidosesR01AR071975 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI SMITH, LACHLAN JAMES · 2017 to 2021
$1.9M
NIAMS NIH HHS R01 AR071975
6 · The paper itself

Abstract

backgroundMorphologic changes in the vertebral body in adolescent idiopathic scoliosis (AIS) have been associated with curve development and progression. Yet, after an AIS spinal surgery, the impact of the global and local spinal realignment on the vertebral body and intervertebral disc morphologic changes, particularly in the distal unfused spine, have not been determined. QUESTIONS/PURPOSES: To determine the changes in the unfused lumbar vertebrae and disc morphology two years after spinal fusion in AIS patients undergoing selective thoracic fusion (STF). PATIENTS AND

methodsA total of 58 patients with Lenke type 1 AIS who underwent STF with a minimum two-year follow-up and 20 nonscoliotic adolescents were included. Biplanar stereoradiography of the spine at preoperative, early postoperative, and two-year follow-up were used to generate 3D models of the spine. Lumbar spine vertebral and intervertebral heights (anterior, posterior, left, and right) and the degree of wedging in the frontal and sagittal plane were calculated in the local coordinate system of the vertebral bodies. The morphology of vertebrae and discs were compared between the pre- and postoperative visits of AIS patients and nonscoliotic controls.

resultsLumbar lordosis was not statistically different between the pre- and post-operative AIS and controls, p > .05. The contribution of the lumbar vertebral bodies and discs' sagittal wedging to the total L1-L5 lordosis were 20% and 80%, respectively, for nonscoliotic controls and 61% and 39%, respectively, for AIS patients at two-year follow-up. The decrease in the anterior and left heights of the disc between the preoperative and two-year follow-up was significant, p < .05.

conclusionPatients undergoing STF for Lenke 1 AIS are able to achieve normal lumbar lordosis after surgery but seem to regain their sagittal alignment by morphologic changes in the disc more so than the vertebral body. A larger contribution of the vertebral sagittal wedging to the total lumbar lordosis at two years post STF was observed when these variables were compared to the nonscoliotic adolescents. LEVEL OF EVIDENCE: Level IV.

Indexed as

Intervertebral DiscSpinal FusionAdolescentBone RemodelingFollow-Up StudiesHumansLordosisScoliosisSpineAdolescent Idiopathic ScoliosisIntervertebral discMorphologySpineVertebra

Identifiers

PMID31495475
PMCPMC11361733
OpenAlexW2972271183

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.