Evidence map›Paper›PMID 31495454›Full record

ArticleTrends in pharmacological sciences2019

The Sodium Channel Voltage Sensor Slides to Rest.

Vladimir Yarov-Yarovoy, Paul DeCaen

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in pharmacological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Vladimir Yarov-YarovoyDepartment of Physiology and Membrane Biology, University of California at Davis, Davis, CA, USA. Electronic address: yarovoy@ucdavis.edu.
Paul DeCaenDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address: Paul.Decaen@northwestern.edu.

Funding

Molecular dysregulation of primary cilia TRPP2 channels caused by Finger 1 variantsR01DK123463 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DECAEN, PAUL GREGORY · 2019 to 2023
$2.0M
The genetic identity of the primary cilia ion channels of kidney collecting duct cells and their regulation by internal calciumR00DK106655 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DECAEN, PAUL GREGORY · 2017 to 2019
$742k
The mechanistic impact of Finger 1 variants on polycystin-2 (PKD2) channels in the primary ciliaR56DK119709 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DECAEN, PAUL GREGORY · 2018 to 2018
$138k
NIDDK NIH HHS R00 DK106655NIDDK NIH HHS R01 DK123463NIDDK NIH HHS R56 DK119709
6 · The paper itself

Abstract

Voltage-gated sodium channels (Na

Indexed as

SodiumVoltage-Gated Sodium ChannelsMolecular ConformationSodiumVoltage-Gated Sodium Channelsgating chargemembrane proteinresting statesodium channelvoltage-dependent channel gatingvoltage-gated ion channel

Identifiers

PMID31495454
PMCPMC7373202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.