ReviewBiological psychiatry. Cognitive neuroscience and neuroimaging2019
Prediction, Psychosis, and the Cerebellum.
Review in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Dissecting Schizophrenia Biology Using Pleiotropy With Cognitive Genomics.Biological psychiatry · 2025Pooled it
- Mentalizing About Dynamic Social Action Sequences Is Supported by the Cerebellum, Basal Ganglia, and Neocortex: A Meta-Analysis of Activation and Connectivity.Human brain mapping · 2024Pooled it
- Cerebellar gray matter volume changes in patients with schizophrenia: A voxel-based meta-analysis.Frontiers in psychiatry · 2022Pooled it
- Sensorimotor circuit connectivity as a candidate biomarker for responsiveness to sertraline in obsessive-compulsive disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Decoding Psychosis Risk: Neuroanatomical Correlates of the NAPLS-2 Calculator in the PRONIA Cohort.Schizophrenia bulletin · 2026Article
- Psychosis and brainstem malformations: A case series.Indian journal of psychiatry · 2026Article
- Cerebellar-Prefrontal Connectivity Predicts Negative Symptom Severity Across the Psychosis Spectrum.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Latent Growth Models of Longitudinal Changes in Functional Connectivity during Early Stage Psychosis.Neuroinformatics · 2025Article
- Illuminating posterior targets for TMS beyond the prefrontal cortex.Nature. Mental health · 2025Article
- Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech.Translational psychiatry · 2025Article
- Divisive attenuation based on noisy sensorimotor predictions accounts for excess variability in self-touch.Journal of neurophysiology · 2025Article
- I fear you're getting too close: neural correlates of personal space violation in paranoia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Volumetric Changes in Cerebellar Transverse Zones: Age and Sex Effects in Health and Neurological Disorders.Human brain mapping · 2025Article
- Deep Learning Cerebellar Magnetic Resonance Imaging Segmentation in Late-Onset GM2 Gangliosidosis: Implications for Phenotype.medRxiv : the preprint server for health sciences · 2025Article
- Reduced Cerebellar Volumes Associate with P300 Amplitude Attenuation in Children with Clinical High Risk for Psychosis and Early Onset Psychosis.Cerebellum (London, England) · 2025Article
- Psychomotor slowing in schizophrenia is associated with aberrant postural control.Schizophrenia (Heidelberg, Germany) · 2024Article
- Cerebellar Neurostimulation for Boosting Social and Affective Functions: Implications for the Rehabilitation of Hereditary Ataxia Patients.Cerebellum (London, England) · 2024Review
- Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC.Patterns (New York, N.Y.) · 2024Article
- Cerebellar Effects on Abnormal Psychomotor Function Are Mediated by Processing Speed in Psychosis Spectrum.Cerebellum (London, England) · 2024Article
- Dissecting Schizophrenia Biology Using Pleiotropy with Cognitive Genomics.medRxiv : the preprint server for health sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
An increasingly influential hypothesis posits that many of the diverse symptoms of psychosis can be viewed as reflecting dysfunctional predictive mechanisms. Indeed, to perceive something is to take a sensory input and make a prediction of the external source of that signal; thus, prediction is perhaps the most fundamental neural computation. Given the ubiquity of prediction, a more challenging problem is to specify the unique predictive role or capability of a particular brain structure. This question is relevant when considering recent claims that one aspect of the predictive deficits observed in psychotic disorders might be related to cerebellar dysfunction, a subcortical structure known to play a critical role in predictive sensorimotor control and perhaps higher-level cognitive function. Here, we review evidence bearing on this question. We first focus on clinical, behavioral, and neuroimaging findings suggesting cerebellar involvement in psychosis and, specifically, schizophrenia. We then review a relatively novel line of research exploring whether computational models of cerebellar motor function can also account for cerebellar involvement in higher-order human cognition, and in particular, language function. We end the review by highlighting some key gaps in these literatures, limitations that currently preclude strong conclusions regarding cerebellar involvement in psychosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.