ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2019
Temporary adhesion of the proseriate flatworm Minona ileanae.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Glycans in adhesion and fertilization: histochemical and ultrastructural insights from the chaetognath Spadella cephaloptera.Frontiers in zoology · 2026Article
- Glycoproteins Involved in Sea Urchin Temporary Adhesion.Marine drugs · 2023Article
- The Involvement of Cell-Type-Specific Glycans inBiomimetics (Basel, Switzerland) · 2022Article
- Sticking Together an Updated Model for Temporary Adhesion.Marine drugs · 2022Article
- Bio-based and bio-inspired adhesives from animals and plants for biomedical applications.Materials today. Bio · 2022Review
- Decoding the byssus fabrication by spatiotemporal secretome analysis of scallop foot.Computational and structural biotechnology journal · 2022Article
- (Un)expected Similarity of the Temporary Adhesive Systems of Marine, Brackish, and Freshwater Flatworms.International journal of molecular sciences · 2021Article
- Exploring the attachment of the Mediterranean medicinal leech (Journal of the Royal Society, Interface · 2020Article
- Molecular insights into the powerful mucus-based adhesion of limpets (Open biology · 2020Article
- Integrative Transcriptome and Proteome Analysis of the Tube Foot and Adhesive Secretions of the Sea UrchinInternational journal of molecular sciences · 2020Article
- Transdisciplinary approaches to the study of adhesion and adhesives in biological systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
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Authors and funding
16 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flatworms can very rapidly attach to and detach from many substrates. In the presented work, we analysed the adhesive system of the marine proseriate flatworm Minona ileanae. We used light-, scanning- and transmission electron microscopy to analyse the morphology of the adhesive organs, which are located at the ventral side of the tail-plate. We performed transcriptome sequencing and differential RNA-seq for the identification of tail-specific transcripts. Using in situ hybridization expression screening, we identified nine transcripts that were expressed in the cells of the adhesive organs. Knock-down of five of these transcripts by RNA interference led to a reduction of the animal's attachment capacity. Adhesive proteins in footprints were confirmed using mass spectrometry and antibody staining. Additionally, lectin labelling of footprints revealed the presence of several sugar moieties. Furthermore, we determined a genome size of about 560 Mb for M. ileanae. We demonstrated the potential of Oxford Nanopore sequencing of genomic DNA as a cost-effective tool for identifying the number of repeats within an adhesive protein and for combining transcripts that were fragments of larger genes. A better understanding of the molecules involved in flatworm bioadhesion can pave the way towards developing innovative glues with reversible adhesive properties. This article is part of the theme issue 'Transdisciplinary approaches to the study of adhesion and adhesives in biological systems'.
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