Evidence map›Paper›PMID 31495281›Full record

ReviewTechnology in cancer research & treatment2019

Artificial Intelligence in Radiotherapy Treatment Planning: Present and Future.

Chunhao Wang, Xiaofeng Zhu, Julian C Hong, Dandan Zheng

Open access · goldAbstract readReview
In one paragraph

Review in Technology in cancer research & treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 1 pooled it
24.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 1 synthesis or guideline pooled it, 230 citations in OpenAlex.

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  12. Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Chunhao Wang1 Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA.ORCID 0000-0002-6945-7119
Xiaofeng Zhu2 Department of Radiation Oncology, Georgetown University Hospital, Rockville, MD, USA.
Julian C Hong1 Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA.ORCID 0000-0001-5172-6889
Dandan Zheng4 Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA.ORCID 0000-0003-2259-1633
Duke Medical Center · USGeorgetown University · USUniversity of California, San Francisco · USUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment planning is an essential step of the radiotherapy workflow. It has become more sophisticated over the past couple of decades with the help of computer science, enabling planners to design highly complex radiotherapy plans to minimize the normal tissue damage while persevering sufficient tumor control. As a result, treatment planning has become more labor intensive, requiring hours or even days of planner effort to optimize an individual patient case in a trial-and-error fashion. More recently, artificial intelligence has been utilized to automate and improve various aspects of medical science. For radiotherapy treatment planning, many algorithms have been developed to better support planners. These algorithms focus on automating the planning process and/or optimizing dosimetric trade-offs, and they have already made great impact on improving treatment planning efficiency and plan quality consistency. In this review, the smart planning tools in current clinical use are summarized in 3 main categories: automated rule implementation and reasoning, modeling of prior knowledge in clinical practice, and multicriteria optimization. Novel artificial intelligence-based treatment planning applications, such as deep learning-based algorithms and emerging research directions, are also reviewed. Finally, the challenges of artificial intelligence-based treatment planning are discussed for future works.

Indexed as

Artificial IntelligenceRadiotherapy Planning, Computer-AssistedAlgorithmsHumansNeoplasmsRadiotherapy DosageWorkflowartificial intelligence machine learning radiotherapy treatment planning automation

Identifiers

PMID31495281
PMCPMC6732844
OpenAlexW2972150145

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.