Evidence map›Paper›PMID 31495193›Full record

ArticleChild maltreatment2019

Childhood Maltreatment, Cortical and Amygdala Morphometry, Functional Connectivity, Laterality, and Psychopathology.

Martin H Teicher, Alaptagin Khan

Open access · greenAbstract readComment
In one paragraph

Article in Child maltreatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

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  5. Attachment orientation and platelet activity.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Martin H TeicherDevelopmental Biopsychiatry Research Program, McLean Hospital, Belmont, MA, USA, and Harvard Medical School, Boston, MA, USA.
Alaptagin KhanDevelopmental Biopsychiatry Research Program, McLean Hospital, Belmont, MA, USA, and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7372-1920
Harvard University · US

Funding

Early Stress, Sensitive Periods and the Neurobiology of AddictionR01DA017846 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI TEICHER, MARTIN H · 2004 to 2024
$9.8M
Neurobiology of Mothering and Infant StressR01HD079484 · NICHD · MCLEAN HOSPITAL · PI BOSQUET ENLOW, MICHELLE A, GRANT, PATRICIA ELLEN · 2015 to 2019
$3.6M
Sensitive Periods, Brain Development and DepressionR01MH091391 · NIMH · MCLEAN HOSPITAL · PI TEICHER, MARTIN H · 2010 to 2014
$3.4M
Effects of Childhood Maltreatment on Research Domain NeurocircuitsR03MH113077 · NIMH · MCLEAN HOSPITAL · PI TEICHER, MARTIN H · 2017 to 2018
$162k
NICHD NIH HHS R01 HD079484NIDA NIH HHS R01 DA017846NIMH NIH HHS R03 MH113077
6 · The paper itself

Abstract

Child maltreatment (CM) is the most important preventable risk factor for psychopathology and there is a pressing need to understand how CM gets 'under the skin' to markedly increase risk in some individuals as well as a comparable effort to identify factors associated with better than expected outcomes in other individuals. This special issue of Child Maltreatment provides a series of sophisticated studies on the neurobiological impact of CM, of which we have chosen 4 articles to comment on.The articles by Oshri et al., and Peveril, Sheridan, Busso & McLaughlin are amygdala centric and provide important new information on the impact of CM on the morphology and functional connectivity of this highly stress susceptible structure. The article by Demers et al., presents data from a longitudinal study that illustrates the potentially disruptive effects of CM on the association between maternal relationship quality, frontal cortical development and symptomatology. Finally, the De Bellis et al., study addresses the pressing question, which we have labeled the 'ecophenotype hypothesis', that postulates that maltreated and non-maltreated individuals with the same primary DSM diagnosis are clinically and neurobiologically distinct, and provides new evidence for a specific prefrontal cortical neurobiological abnormality in the maltreated subtype.

Indexed as

AlcoholismChild AbuseAdolescentAmygdalaBrainChildHippocampusHumansLongitudinal StudiesMagnetic Resonance ImagingPilot ProjectsPsychopathologyadverse childhood experienceschild maltreatmentcognitive developmentresilience

Identifiers

PMID31495193
PMCPMC8140519
OpenAlexW2971476031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.