Evidence map›Paper›PMID 31495081›Full record

ArticleExperimental neurobiology2019

Calpain-2 as a Treatment Target in Prenatal Stress-induced Epileptic Spasms in Infant Rats.

Hyeok Hee Kwon, Chiranjivi Neupane, Juhee Shin, Do Hyeong Gwon, Yuhua Yin, Nara Shin, Hyo Jung Shin, Jinpyo Hong, Jin Bong Park, YoonYoung Yi and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Hyeok Hee KwonDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Chiranjivi NeupaneDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Juhee ShinDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Do Hyeong GwonDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Yuhua YinDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Nara ShinDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Hyo Jung ShinDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Jinpyo HongDepartment of Anatomy, School of Medicine, Chungnam National University, Daejeon 35015, Korea.
Jin Bong ParkDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
YoonYoung YiDepartment of Pediatrics, Chungnam National University Hospital, Daejeon 35015, Korea.
Dong Woon KimDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Joon Won KangDepartment of Medical Science, Chungnam National University, Daejeon 35015, Korea.
Chungnam National University · KRChungnam National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress can induce a serious epileptic encephalopathy that occurs during early infancy. Recent studies have revealed that prenatal stress exposure is a risk factor for the development of infantile spasms. Our previous work demonstrates that prenatal stress with betamethasone-induced alterations to the expression of the K

Indexed as

CalpainEpilepsyGlutamate decarboxylase 67KCC2K+/Cl- co-transporterNMDA

Identifiers

PMID31495081
PMCPMC6751866
OpenAlexW2969627113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.