Evidence map›Paper›PMID 31494953›Full record

ArticleMedical physics2019

Effect of source blur on digital breast tomosynthesis reconstruction.

Jiabei Zheng, Jeffrey A Fessler, Heang-Ping Chan

Abstract read
In one paragraph

Article in Medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Hybrid simulation of breast CT for assessing microcalcification detectability.Journal of medical imaging (Bellingham, Wash.) · 2025
    Article
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  4. Journal of medical imaging (Bellingham, Wash.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiabei ZhengDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Jeffrey A FesslerDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Heang-Ping ChanDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.

Funding

Improvement of microcalcification detection in digital breast tomosynthesisR01CA151443 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHAN, HEANG-PING · 2011 to 2015
$3.0M
Advanced breast tomosynthesis reconstruction for improved cancer diagnosisR01CA214981 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHAN, HEANG-PING, FESSLER, JEFFREY A · 2018 to 2022
$2.3M
NCI NIH HHS R01 CA151443NCI NIH HHS R01 CA214981NIH HHS R01 CA151443NIH HHS R01 CA214981
6 · The paper itself

Abstract

purposeMost digital breast tomosynthesis (DBT) reconstruction methods neglect the blurring of the projection views caused by the finite size or motion of the x-ray focal spot. This paper studies the effect of source blur on the spatial resolution of reconstructed DBT using analytical calculation and simulation, and compares the influence of source blur over a range of blurred source sizes.

methodsMathematically derived formulas describe the point spread function (PSF) of source blur on the detector plane as a function of the spatial locations of the finite-sized source and the object. By using the available technical parameters of some clinical DBT systems, we estimated the effective source sizes over a range of exposure time and DBT scan geometries. We used the CatSim simulation tool (GE Global Research, NY) to generate digital phantoms containing line pairs and beads at different locations and imaged with sources of four different sizes covering the range of potential source blur. By analyzing the relative contrasts of the test objects in the reconstructed images, we studied the effect of the source blur on the spatial resolution of DBT. Furthermore, we simulated a detector that rotated in synchrony with the source about the rotation center and calculated the spatial distribution of the blurring distance in the imaged volume to estimate its influence on source blur.

resultsCalculations demonstrate that the PSF is highly shift-variant, making it challenging to accurately implement during reconstruction. The results of the simulated phantoms demonstrated that a typical finite-sized focal spot (~0.3 mm) will not affect the reconstructed image resolution if the x-ray tube is stationary during data acquisition. If the x-ray tube moves during exposure, the extra blur due to the source motion may degrade image resolution, depending on the effective size of the source along the direction of the motion. A detector that rotates in synchrony with the source does not reduce the influence of source blur substantially.

conclusionsThis study demonstrates that the extra source blur due to the motion of the x-ray tube during image acquisition substantially degrades the reconstructed image resolution. This effect cannot be alleviated by rotating the detector in synchrony with the source. The simulation results suggest that there are potential benefits of modeling the source blur in image reconstruction for DBT systems using continuous-motion acquisition mode.

Indexed as

ArtifactsImage Processing, Computer-AssistedMammographyMotionPhantoms, Imagingdigital breast tomosynthesisgeometric unsharpnessimage reconstructionspatial resolutionx-ray focal spot blur

Identifiers

PMID31494953
PMCPMC6899200

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.