Evidence map›Paper›PMID 31494842›Full record

ArticleNeurotoxicity research2020

Mitochondrial Protection Promoted by the Coffee Diterpene Kahweol in Methylglyoxal-Treated Human Neuroblastoma SH-SY5Y Cells.

Marcos Roberto de Oliveira, Izabel Cristina Custódio de Souza, Cristina Ribas Fürstenau

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. [Kahweol improves motor function of mice with spinal cord injury by inhibiting microglial activationNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Neuroprotective Effects of Coffee Bioactive Compounds: A Review.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcos Roberto de OliveiraGrupo de Estudos em Neuroquímica e Neurobiologia de Moléculas Bioativas, Universidade Federal de Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, 2367, Cuiaba, MT, CEP 78060-900, Brazil. mrobioq@gmail.com.ORCID http://orcid.org/0000-0003-2414-6605
Izabel Cristina Custódio de SouzaPrograma de Pós-Graduação em Bioquímica e Bioprospecção (PPGBBIO), Centro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Instituto de Biologia, Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brazil.
Cristina Ribas FürstenauCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 400216/2016-7Conselho Nacional de Desenvolvimento Científico e Tecnológico 460903/2014-4Conselho Nacional de Desenvolvimento Científico e Tecnológico Bolsa de Produtividade em Pesquisa 2 - PQ2
6 · The paper itself

Abstract

The coffee diterpene kahweol (KW; C

Indexed as

CytoprotectionAdenosine TriphosphateCell Line, TumorDiterpenesDose-Response Relationship, DrugElectron Transport Complex IHumansMembrane Potential, MitochondrialMitochondriaMitochondrial DiseasesNeuroprotective AgentsNF-E2-Related Factor 2PyruvaldehydeReactive Nitrogen SpeciesReactive Oxygen SpeciesSignal TransductionAdenosine TriphosphateDiterpenesElectron Transport Complex IkahweolNeuroprotective AgentsNFE2L2 protein, humanNF-E2-Related Factor 2PyruvaldehydeReactive Nitrogen SpeciesReactive Oxygen SpeciesAntioxidantCytoprotectionKahweolMethylglyoxalMitochondriaNrf2

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.