Evidence map›Paper›PMID 31494682›Full record

ArticleExperimental brain research2019

Three-week treadmill training changes the electrophysiological properties of spinal interneurons in the mice.

Ke Chen, Renkai Ge, Yi Cheng, Yue Dai

Abstract read
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In one paragraph

Article in Experimental brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ke ChenShanghai Key Laboratory of Multidimensional Information Processing, School of Communication and Electronic Engineering, East China Normal University, Shanghai, 200241, China.
Renkai GeShanghai Key Laboratory of Multidimensional Information Processing, School of Communication and Electronic Engineering, East China Normal University, Shanghai, 200241, China.
Yi ChengKey Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education, School of Physical Education and Health Care, East China Normal University, Shanghai, 200241, China.
Yue DaiShanghai Key Laboratory of Multidimensional Information Processing, School of Communication and Electronic Engineering, East China Normal University, Shanghai, 200241, China. ydai@tyxx.ecnu.edu.cn.ORCID http://orcid.org/0000-0002-1773-5228
East China Normal University · CNEast China Jiaotong University · CN

Funding

Major Research Plan 31571222
6 · The paper itself

Abstract

It was shown in previous studies that endurance training enhanced excitability of rat spinal motoneurons. However, the influence of the training on the spinal interneurons remains unclear. In this study, we investigated the training effects on spinal interneurons in dorsal and ventromedial area in mice (P42-P50). The electrophysiological properties of the interneurons were recorded from spinal cord slices (T13-L6) by whole-cell patch-clamp recording. The interneurons could be classified into three types based on their response to step currents: single spike (type 1), phasic firing (type 2), and tonic firing (type 3) in both control and trained mice. Interneurons collected from control mice possessed rheobase of 11.3 ± 6.0 pA and voltage threshold (V

Indexed as

AnimalsElectrophysiological PhenomenaInterneuronsMicePatch-Clamp TechniquesPhysical Conditioning, AnimalRunningSpinal Cord5-HT modulationLocomotionSpinal interneuronTreadmill training

Identifiers

PMID31494682
OpenAlexW2971669944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.