Evidence map›Paper›PMID 31493399›Full record

ArticleGastroenterology2019

Ca

Aran Son, Malini Ahuja, Daniella M Schwartz, Arpad Varga, William Swaim, Namju Kang, Jozsef Maleth, Dong Min Shin, Shmuel Muallem

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Store-operated CaPNAS nexus · 2023
    Article
  11. Article
  12. Review
  13. A microRNA checkpoint for CaMolecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
  14. [Role of CaMK II in pancreatic injury in mice with severe acute pancreatitis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Aran SonEpithelial Signaling and Transport Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Malini AhujaEpithelial Signaling and Transport Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Daniella M SchwartzGenetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Arpad VargaHAS-USZ Momentum Epithelial Cell Signaling and Secretion Research Group, First Department of Medicine, University of Szeged, Szeged, Hungary.
William SwaimNIDCR imaging core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Namju KangDepartment of Oral Biology, BK 21 PLUS Project, Yonsei University College of Dentistry, Seoul, South Korea.
Jozsef MalethHAS-USZ Momentum Epithelial Cell Signaling and Secretion Research Group, First Department of Medicine, University of Szeged, Szeged, Hungary.
Dong Min ShinDepartment of Oral Biology, BK 21 PLUS Project, Yonsei University College of Dentistry, Seoul, South Korea. Electronic address: dmshin@yuhs.ac.
Shmuel MuallemEpithelial Signaling and Transport Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland. Electronic address: Shmuel.muallem@nih.gov.
National Institutes of Health · USUniversity of Szeged · HUYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimsPancreatitis is characterized by increased influx of Ca

methodsWe generated mice that expressed SARAF tagged with hemagglutinin, using CRISPR/Cas9 gene editing, and isolated acinar cells. We also performed studies with Saraf

resultsPancreatic levels of Ca

conclusionsIn mice with pancreatitis, SARAF initially increases but is then degraded, resulting in excessive, pathological Ca

Indexed as

Acinar CellsAnimalsCalciumCeruletideDisease Models, AnimalHEK293 CellsHumansIntracellular Calcium-Sensing ProteinsMembrane ProteinsMiceMice, KnockoutNeoplasm ProteinsPancreasPancreatitisSeverity of Illness IndexStromal Interaction Molecule 1CalciumCeruletideIntracellular Calcium-Sensing ProteinsMembrane ProteinsNeoplasm ProteinsSARAF protein, humanSTIM1 protein, humanStromal Interaction Molecule 1CalciumInjuryPancreasSARAF

Identifiers

PMID31493399
OpenAlexW2971376202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.