Evidence map›Paper›PMID 31493324›Full record

ArticleJMIR research protocols2019

Exploring Severe Mental Illness and Diabetes: Protocol for a Longitudinal, Observational, and Qualitative Mixed Methods Study.

Sue Bellass, Johanna Taylor, Lu Han, Stephanie L Prady, David Shiers, Rowena Jacobs, Richard Ian Gregory Holt, John Radford, Simon Gilbody, Catherine Hewitt and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03534921 (Improving Diabetes Outcomes for People With Severe Mental Illness), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03534921 completednot on this map

Improving Diabetes Outcomes for People With Severe Mental Illness (SMI): a Longitudinal Observational and Qualitative Study of Patients in England

TypeobservationalSponsorUniversity of YorkRan2018 to 2019Enrolled46,564ConditionsDiabetes Mellitus, Type 2, Severe Mental Disorder
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Sue BellassMental Health and Addiction Research Group, Department of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0001-9383-4116
Johanna TaylorDepartment of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0001-5898-0900
Lu HanMental Health and Addiction Research Group, Department of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0001-7198-3380
Stephanie L PradyDepartment of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0002-8933-8045
David ShiersPsychosis Research Unit, Prestwich Hospital, Greater Manchester Mental Health NHS Foundation Trust & The University of Manchester, Manchester, United Kingdom.ORCID 0000-0003-2531-5837
Rowena JacobsCentre for Health Economics, Department of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0001-5225-6321
Richard Ian Gregory HoltFaculty of Medicine, University of Southampton, Southampton, United Kingdom.ORCID 0000-0001-8911-6744
John RadfordDIAMONDS VOICE Patient and Public Involvement Panel, Bradford District Care NHS Foundation Trust, Bradford, Bradford, United Kingdom.ORCID 0000-0003-1526-6453
Simon GilbodyMental Health and Addiction Research Group, Department of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0002-8236-6983
Catherine HewittYork Trials Unit, Department of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0002-0415-3536
Tim DoranDepartment of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0001-7857-3704
Sarah L AldersonFaculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.ORCID 0000-0002-5418-0495
Najma SiddiqiMental Health and Addiction Research Group, Department of Health Sciences, University of York, York, United Kingdom.ORCID 0000-0003-1794-2152
University of York · GBBradford District Care NHS Foundation Trust · GBGreater Manchester Mental Health NHS Foundation Trust · GBUniversity of Leeds · GBUniversity of Southampton · GB

Funding

Department of Health 15/70/26Department of Health HS&DR/15/70/26
6 · The paper itself

Abstract

backgroundThe average life expectancy for people with a severe mental illness (SMI) such as schizophrenia or bipolar disorder is 15 to 20 years less than that for the population as a whole. Diabetes contributes significantly to this inequality, being 2 to 3 times more prevalent in people with SMI. Various risk factors have been implicated, including side effects of antipsychotic medication and unhealthy lifestyles, which often occur in the context of socioeconomic disadvantage and health care inequality. However, little is known about how these factors may interact to influence the risk of developing diabetes and poor diabetic outcomes, or how the organization and provision of health care may contribute.

objectiveThis study aims to identify the determinants of diabetes and to explore variation in diabetes outcomes for people with SMI.

methodsThis study will employ a concurrent mixed methods design combining the interrogation of electronic primary care health records from the Clinical Practice Research Datalink (CPRD GOLD) with qualitative interviews with adults with SMI and diabetes, their relatives and friends, and health care staff. The study has been funded for 2 years, from September 2017 to September 2019, and data collection has recently ended.

resultsCPRD and linked health data will be used to explore the association of sociodemographics, illness, and health care-related factors with both the development and outcomes of type 2 diabetes in people with SMI. Experiences of managing the comorbidity and accessing health care will be explored through qualitative interviews using topic guides informed by evidence synthesis and expert consultation. Findings from both datasets will be merged to develop a more comprehensive understanding of diabetes risks, interventions, and outcomes for people with SMI. Findings will be translated into recommendations for interventions and services using co-design workshops.

conclusionsImproving diabetes outcomes for people with SMI is a high-priority area nationally and globally. Understanding how risk factors combine to generate high prevalence of diabetes and poor diabetic outcomes for this population is a necessary first step in developing health care interventions to improve outcomes for people with diabetes and SMI.

trial registrationClinicalTrials.gov NCT03534921; https://clinicaltrials.gov/ct2/show/NCT03534921.

Indexed as

bipolar disorderdiabetes complicationsdiabetes mellitusschizophrenia

Identifiers

PMID31493324
PMCPMC6786849
OpenAlexW2941854324

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.