Evidence map›Paper›PMID 31493285›Full record

ArticleMolecular biology reports2019

Evaluation of protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside against mercuric chloride-induced nephrotoxicity in rats.

Tareq Aqeel, Sunil Chikkalakshmipura Gurumallu, Saeed Mujahid Hashimi, Naif AlQurashi, Rajesh Javaraiah

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Amelioration of oxidative kidney damage in offspring by maternal trans-fatty acid exposure in mice by secoisolariciresinol diglucoside.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Tareq AqeelDepartment of Biochemistry, Yuvaraja's College, University of Mysore, Mysuru, Karnataka, 570005, India.
Sunil Chikkalakshmipura GurumalluDepartment of Biochemistry, Yuvaraja's College, University of Mysore, Mysuru, Karnataka, 570005, India.
Saeed Mujahid HashimiDepartment of Basic Science, Biology Unit Deanship of Preparatory Year and Supporting studies, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam, 34212, Saudi Arabia.
Naif AlQurashiDepartment of Basic Science, Biology Unit Deanship of Preparatory Year and Supporting studies, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam, 34212, Saudi Arabia.
Rajesh JavaraiahDepartment of Biochemistry, Yuvaraja's College, University of Mysore, Mysuru, Karnataka, 570005, India. rajeshj11@rediffmail.com.ORCID http://orcid.org/0000-0002-6965-5131
University of Mysore · INImam Abdulrahman Bin Faisal University · SA

Funding

Department of Science and Technology, Government of India, New Delhi SR/FT/LS-047/2009
6 · The paper itself

Abstract

The toxicity of heavy metals such as mercury (Hg) in humans and animals is well documented. The kidney is the primary deposition site of inorganic-Hg and target organ of its toxicity. The present study investigated the protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside (SDG) on nephrotoxicity induced by mercuric chloride (HgCl

Indexed as

AnimalsAntioxidantsBiomarkersButylene GlycolsChromatography, High Pressure LiquidFlaxGlucosidesGlutathione TransferaseKidneyLignansMaleMercuric ChlorideMolecular StructureOxidative StressPlant ExtractsProtective AgentsAntioxidantsBiomarkersButylene GlycolsGlucosidesGlutathione TransferaseLignansMercuric ChloridePlant ExtractsProtective Agentssecoisolariciresinol diglucosideFlaxseed lignanMercuric chlorideNephrotoxicityOxidative stressSecoisolariciresinol diglucoside

Identifiers

PMID31493285
OpenAlexW2971628518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.