Evidence map›Paper›PMID 31493193›Full record

ArticleWorld journal of surgery2019

Outcomes Following Major Oncologic Operations for Non-AIDS-Defining Cancers in the HIV Population: A Matched Comparison to the General Population.

Amber Chi, Bryan E Adams, Joanna Sesti, Subroto Paul, Amber L Turner, David August, Darren Carpizo, Timothy Kennedy, Miral Grandhi, H Richard Alexander and 3 more

Abstract read
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Article in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Amber ChiDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Bryan E AdamsDepartment of Mathematical Sciences, United States Military Academy, West Point, NY, USA.
Joanna SestiDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Subroto PaulDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Amber L TurnerDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
David AugustDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Darren CarpizoDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Timothy KennedyDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Miral GrandhiDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
H Richard AlexanderDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Steven K LibuttiDivision of Surgical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Stuart GeffnerDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA.
Russell C LanganDepartment of Surgery, Saint Barnabas Medical Center, RWJBarnabas Health, Livingston, NJ, USA. russell.langan@rwjbh.org.
Saint Barnabas Medical Center · USRutgers Cancer Institute of New JerseyRutgers, The State University of New Jersey · USUnited States Military Academy · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHuman immunodeficiency virus (HIV) patients are living longer due to the availability of antiretroviral therapies, and non-AIDS-defining cancers are becoming more prevalent in this patient population. A paucity of data remains on post-operative outcomes following resection of non-AIDS-defining cancers in the HIV population.

methodsThe National Inpatient Sample was utilized to identify patients who underwent surgical resection for malignancy from 2005 to 2015 (HIV, N = 52,742; non-HIV, N = 11,885,184). Complications were categorized by international classification of disease (ICD)-9 diagnosis codes. Cohorts were matched on insurance, household income, zip code and urban/rural setting. Logistic regression assessed whether HIV was an independent predictor of post-operative complications.

resultsDescriptive statistics found HIV patients to have an increased rate of complications following select oncologic surgical resections. Univariate and multivariate logistic regression found HIV to only be an independent predictor of complications following pulmonary lobectomy (p = 0.011; OR 2.93, 95% CI 1.29-6.73). Length of stay was statistically longer following colectomy (2.61 days, 95% CI 1.98-3.44) in those with HIV.

conclusionsOur findings are hypothesis generating and highlight the potential safety of major cancer surgery in the HIV population. However, care providers need be cognizant of the potential increased risk of post-operative complications following pulmonary lobectomy and the potential for increased length of stay. These findings are an initial insight into quality of care and outcomes metrics on HIV patients undergoing major cancer operations.

Indexed as

AdolescentAdultAgedFemaleHIV InfectionsHumansLength of StayMaleMiddle AgedNeoplasmsPostoperative ComplicationsRisk AssessmentRisk FactorsTreatment OutcomeUnited StatesYoung Adult

Identifiers

PMID31493193
OpenAlexW2971924213

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.