ArticleEuropean journal of epidemiology2019
Validation of multiple sclerosis diagnoses in the Swedish National Patient Register.
Article in European journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Case Definitions and Data Sources for NNCSS Parkinson Disease Surveillance: A Systematic Review.JAMA network open · 2026Pooled it
- Maternal autoimmune diseases during pregnancy and mortality up to young adulthood in offspring: a register-based cohort study.EClinicalMedicine · 2026Article
- A susceptibility network analysis of disease trajectories leading to multiple sclerosis: A nationwide cohort study.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- Body mass index and the risk of ulnar nerve entrapment in individuals without diabetes-a longitudinal cohort study from Sweden.International journal of obesity (2005) · 2025Article
- Prodromal phase of multiple sclerosis: evidence from sickness absence patterns before disease onset - a matched cohort study.Journal of neurology, neurosurgery, and psychiatry · 2025Article
- The association between poor dental health and gastric cancer risk: a nationwide cohort and sibling-controlled study.BMC medicine · 2025Article
- Kappa Free Light Chain Index Correlates With Prognostic Biomarkers in Multiple Sclerosis and Decreases Slowly Following Treatment.European journal of neurology · 2025Article
- Pediatric obesity and the risk of multiple sclerosis: a nationwide prospective cohort study.International journal of obesity (2005) · 2025Article
- Changes in the prevalence of maternal chronic conditions during pregnancy: A nationwide age-period-cohort analysis.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Sex differences in the impact of lower respiratory tract infections on older adults' health trajectories: a population-based cohort study.BMC infectious diseases · 2024Article
- Building and validating trend-based multiple sclerosis case definitions: a population-based cohort study for Manitoba, Canada.BMJ open · 2024Article
- Incidence rate and prevalence of pediatric-onset multiple sclerosis in Sweden: A population-based register study.European journal of neurology · 2024Article
- Bidirectional association between autoimmune disease and perinatal depression: a nationwide study with sibling comparison.Molecular psychiatry · 2024Article
- The global patient-reported outcomes for multiple sclerosis initiative: bridging the gap between clinical research and care - updates at the 2023 plenary event.Frontiers in neurology · 2024Review
- Trend control charts for multiple sclerosis case definitions.International journal of population data science · 2024Article
- Excess costs of multiple sclerosis: a register-based study in Sweden.The European journal of health economics : HEPAC : health economics in prevention and care · 2023Observational
- Performance of administrative databases for identifying individuals with multiple sclerosis.Scientific reports · 2023Article
- Validity of distal radius fracture diagnoses in the Swedish National Patient Register.European journal of medical research · 2023Article
- Spasticity treatment patterns among people with multiple sclerosis: a Swedish cohort study.Journal of neurology, neurosurgery, and psychiatry · 2023Article
- B-cell repopulation dynamics and drug pharmacokinetics impact SARS-CoV-2 vaccine efficacy in anti-CD20-treated multiple sclerosis patients.European journal of neurology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Population-based registers are widely used in epidemiological studies. We aimed to estimate the validity of multiple sclerosis (MS) diagnoses registered in the Swedish National Patient Register (NPR) by two sequential register-based case-definition algorithms. Prevalent MS patients aged 16-64 years were identified from the in- and specialised out-patient NPR in 2001-2013, using International Classification of Diseases code G35. These identified MS diagnoses were validated through two sequential register-based case-definition algorithms, as the 'gold-standard' reference, by linking individual-level data longitudinally to other nationwide registers. The primary algorithm first sought to corroborate the MS diagnoses with MS-specific information in other nationwide registers. The exploratory secondary algorithm identified individuals with MS-related information in other registers and those who were unable to be followed sufficiently. Through multi-register linkage, we estimated the number of confirmed and uncertain individuals with an MS diagnosis recorded in the NPR. A total of 19,781 individuals (mean age at first visit 45.2 years; 69.5% women) had at least one MS diagnosis recorded in the NPR during 2001-2013. Using the two case-definition algorithms, 92.5% (n = 18,291) of the MS diagnoses recorded in the NPR were confirmed, while 7.5% (n = 1490) remained uncertain. Our findings indicate that a very high percentage of patients coded with an MS diagnosis in the Swedish NPR actually have MS, and supports the use of the NPR as a viable source to identify individuals with an MS diagnosis for population-based research. This exploratory methods paper suggests an alternative novel method to verify individuals' diagnoses in register-based settings.
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