Evidence map›Paper›PMID 31493142›Full record

ReviewWorld journal of microbiology & biotechnology2019

An overview on anti-biofilm properties of quercetin against bacterial pathogens.

Hamed Memariani, Mojtaba Memariani, Abdolmajid Ghasemian

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 125 citations in OpenAlex.

  1. Article
  2. Article
  3. Combined use of methyl gallate and N-acyl homoserine lactonase YtnP to inhibit biofilm formation in Burkholderia thailandensis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
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  6. Article
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  8. Article
  9. Review
  10. Phytochemical Composition and Biological Properties ofAntioxidants (Basel, Switzerland) · 2025
    Article
  11. Review
  12. Article
  13. Antibacterial and antibiofilm activities and mechanisms ofCurrent research in food science · 2025
    Article
  14. Drug design, development and therapy · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Hamed MemarianiSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mojtaba MemarianiSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. memaryani@gmail.com.ORCID http://orcid.org/0000-0002-4964-3117
Abdolmajid GhasemianDepartment of Microbiology, Fasa University of Medical Sciences, Fasa, Iran.
Fasa University of Medical Sciences · IRShahid Beheshti University · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial biofilms are multicellular aggregates enclosed in a self-created biopolymer matrix. Biofilm-producing bacteria have become a great public health problem worldwide because biofilms enable these microorganisms to evade several clearance mechanisms produced by host and synthetic sources. Over the past years, different flavonoids including quercetin have engrossed considerable interest among researchers owing to their potential anti-biofilm properties. To our knowledge, there is no review regarding effects of quercetin towards bacterial biofilms, prompting us to summarize experimental evidence on its anti-biofilm properties. Quercetin inhibits biofilm development by a diverse array of bacterial pathogens such as Enterococcus faecalis, Staphylococcus aureus, Streptococcus mutans, Escherichia coli, and Pseudomonas aeruginosa. Prevention of bacterial adhesion, suppression of quorum-sensing pathways, disruption or alteration of plasma membrane, inhibition of efflux pumps, and blocking nucleic acid synthesis have been documented as major anti-biofilm mechanisms of quercetin. Overall, anti-biofilm activity of quercetin can open up new horizons in a wide range of biomedical areas, from food industry to medicine.

Indexed as

BacteriaBacterial AdhesionBiofilmsCell MembraneCell WallMicrobial Sensitivity TestsNucleic AcidsNucleic Acid Synthesis InhibitorsQuercetinQuorum SensingNucleic AcidsNucleic Acid Synthesis InhibitorsQuercetinAdhesionAnti-biofilmBacteriaQuercetinQuorum-sensing

Identifiers

PMID31493142
OpenAlexW2971403604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.