ReviewJournal of ophthalmic inflammation and infection2019
Paradoxical reactions in ocular tuberculosis.
Review in Journal of ophthalmic inflammation and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Incidental Papilledema Revealing Neurotuberculosis: A Case Report of a Diagnostic Challenge.Diagnostics (Basel, Switzerland) · 2026Article
- Vestibulocochlear Neuritis as a Paradoxical Reaction in an Immunocompetent Patient with Tuberculous Meningitis.Diagnostics (Basel, Switzerland) · 2025Article
- A Rare Paradoxical Reaction in Cutaneous Tuberculosis: Insight from a Case of Lupus Vulgaris.Clinical, cosmetic and investigational dermatology · 2025Article
- State-of-the-Art Review: Ocular Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Infectious eye disease in the 21st century-an overview.Eye (London, England) · 2024Review
- Presumed ocular tuberculosis - need for caution before considering anti-tubercular therapy.Eye (London, England) · 2023Article
- Case Report: Community-Acquired Burkholderia cepacia Pneumonia of a Patient with Pulmonary Tuberculosis.The American journal of tropical medicine and hygiene · 2022Article
- Commentary: Importance of ocular imaging in macular serpiginous choroiditis.Indian journal of ophthalmology · 2022Article
- A case and literature review of intraocular echinococcus causing bilateral visual loss in a HIV-infected patient.SAGE open medical case reports · 2022Article
- Ocular manifestations and refractive errors among people living with HIV in Pune, India: a cross-sectional study.The Journal of international medical research · 2021Article
- [Treatment of ocular tuberculosis-an update].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Review
- Simultaneous mutually exclusive active tubercular posterior uveitis.Indian journal of ophthalmology · 2020Article
- Coats-like response in tubercular subretinal abscess masquerading as melanoma as the initial manifestation of miliary tuberculosis.Indian journal of ophthalmology · 2020Article
- Tubercular panophthalmitis in a patient with human immunodeficiency virus infection: Proven clinicopathologically and by molecular diagnostic tests.Indian journal of ophthalmology · 2020Article
- Human immunodeficiency virus and intraocular inflammation in the era of highly active anti retroviral therapy - An update.Indian journal of ophthalmology · 2020Review
- Interleukins and cytokine biomarkers in uveitis.Indian journal of ophthalmology · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paradoxical reactions following initiation of anti-tubercular therapy have been documented most often in extrapulmonary tuberculosis. A combination of factors such as delayed hypersensitivity, decreased suppressor mechanisms, and an increased response to mycobacterial antigens mediated by the host's immune system have been implicated in the development of these reactions. Similar worsening in patients with ocular tuberculosis while on treatment has been described. It is therefore important for the clinician to be aware of this occurrence, as prompt recognition and timely institution of corticosteroids and immunosuppressants can lead to restoration of vision. In these patients, an alteration or discontinuation of anti-tubercular therapy may not be indicated.
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