Evidence map›Paper›PMID 31492844›Full record

ArticleNature communications2019

An ancestral NB-LRR with duplicated 3'UTRs confers stripe rust resistance in wheat and barley.

Chaozhong Zhang, Lin Huang, Huifei Zhang, Qunqun Hao, Bo Lyu, Meinan Wang, Lynn Epstein, Miao Liu, Chunlan Kou, Juan Qi and 13 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 1 pooled it
28.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 1 synthesis or guideline pooled it, 193 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. High‑density mapping of stripe rust resistance gene YrH8 in wheat line Hangmai 8.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
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  10. Unveiling the genetic architecture of stripe rust resistance in wheat: a region-specific GWAS in Xinjiang, China.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  11. Review
  12. Review
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  14. Assessment of genomic prediction capabilities of transcriptome data in a barley multi-parent RIL population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  15. Molecular characterization of a new wheat-Thinopyrum ponticum translocation line with resistance to stripe rust.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 2 countries.

Chaozhong ZhangState Key Laboratory of Crop Biology, Shandong Agricultural University, 271018, Tai'an, Shandong, China.ORCID http://orcid.org/0000-0002-0247-3771
Lin HuangTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China.
Huifei ZhangDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.
Qunqun HaoDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.
Bo LyuDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.
Meinan WangDepartment of Plant Pathology, Washington State University, Pullman, WA, 99164, USA.
Lynn EpsteinDepartment of Plant Pathology, University of California, Davis, CA, 95616, USA.ORCID http://orcid.org/0000-0001-8697-1227
Miao LiuTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0002-0883-4750
Chunlan KouTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China.
Juan QiState Key Laboratory of Crop Biology, Shandong Agricultural University, 271018, Tai'an, Shandong, China.ORCID http://orcid.org/0000-0002-3091-3885
Fengjuan ChenState Key Laboratory of Crop Biology, Shandong Agricultural University, 271018, Tai'an, Shandong, China.
Mengkai LiState Key Laboratory of Crop Biology, Shandong Agricultural University, 271018, Tai'an, Shandong, China.
Ge GaoState Key Laboratory of Crop Biology, Shandong Agricultural University, 271018, Tai'an, Shandong, China.
Fei NiState Key Laboratory of Crop Biology, Shandong Agricultural University, 271018, Tai'an, Shandong, China.ORCID http://orcid.org/0000-0002-7976-6855
Lianquan ZhangTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0001-9005-8705
Ming HaoTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China.
Jirui WangTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China.
Xianming ChenWheat Health, Genetics, and Quality Research Unit, USDA-ARS, Pullman, WA, 99164, USA.ORCID http://orcid.org/0000-0002-9013-5974
Ming-Cheng LuoDepartment of Plant Sciences, University of California, Davis, CA, 95616, USA.ORCID http://orcid.org/0000-0002-9744-5887
Youliang ZhengTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China.
Jiajie WuState Key Laboratory of Crop Biology, Shandong Agricultural University, 271018, Tai'an, Shandong, China. jiajiewu@sdau.edu.cn.ORCID http://orcid.org/0000-0002-1536-2421
Dengcai LiuTriticeae Research Institute, Sichuan Agricultural University, 611130, Chengdu, Sichuan, China. dcliu7@yahoo.com.ORCID http://orcid.org/0000-0001-5508-1125
Daolin FuDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA. dlfu@uidaho.edu.ORCID http://orcid.org/0000-0002-1870-2989
Sichuan Agricultural University · CNShandong Agricultural University · CNUniversity of Idaho · USUniversity of California, Davis · USQuality Research · USWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a global threat to wheat production. Aegilops tauschii, one of the wheat progenitors, carries the YrAS2388 locus for resistance to Pst on chromosome 4DS. We reveal that YrAS2388 encodes a typical nucleotide oligomerization domain-like receptor (NLR). The Pst-resistant allele YrAS2388R has duplicated 3' untranslated regions and is characterized by alternative splicing in the nucleotide-binding domain. Mutation of the YrAS2388R allele disrupts its resistance to Pst in synthetic hexaploid wheat; transgenic plants with YrAS2388R show resistance to eleven Pst races in common wheat and one race of P. striiformis f. sp. hordei in barley. The YrAS2388R allele occurs only in Ae. tauschii and the Ae. tauschii-derived synthetic wheat; it is absent in 100% (n = 461) of common wheat lines tested. The cloning of YrAS2388R will facilitate breeding for stripe rust resistance in wheat and other Triticeae species.

Indexed as

3' Untranslated RegionsAllelesBasidiomycotaChromosome MappingDisease ResistanceGene DuplicationGene Expression Regulation, PlantGenes, PlantHordeumMutationPhylogenyPlant DiseasesPlants, Genetically ModifiedTriticum3' Untranslated Regions

Identifiers

PMID31492844
PMCPMC6731223
OpenAlexW2972257072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.