Evidence map›Paper›PMID 31492761›Full record

ReviewJournal of epidemiology and community health2019

How do early-life factors explain social inequalities in adolescent mental health? Findings from the UK Millennium Cohort Study.

Viviane S Straatmann, Eric Lai, Theis Lange, Melisa Claire Campbell, Sophie Wickham, Anne-Marie Nybo Andersen, Katrine Strandberg-Larsen, David Taylor-Robinson

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of epidemiology and community health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Psychosocial health and quality of life in ICSI and naturally conceived adolescents: a cross-sectional comparison.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Viviane S StraatmannPublic Health and Policy, Institute of Psychology Health and Society, University of Liverpool, Liverpool, UK v.schultz-straatmann@liv.ac.uk.ORCID 0000-0003-2355-1174
Eric LaiPublic Health and Policy, Institute of Psychology Health and Society, University of Liverpool, Liverpool, UK.
Theis LangeCenter for Statistical Science, Peking University, Beijing, China.
Melisa Claire CampbellPublic Health and Policy, Institute of Psychology Health and Society, University of Liverpool, Liverpool, UK.
Sophie WickhamPublic Health and Policy, Institute of Psychology Health and Society, University of Liverpool, Liverpool, UK.
Anne-Marie Nybo AndersenDepartment of Public Health, Section of Social Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-4296-8488
Katrine Strandberg-LarsenDepartment of Public Health, Section of Social Medicine, University of Copenhagen, Copenhagen, Denmark.
David Taylor-RobinsonPublic Health and Policy, Institute of Psychology Health and Society, University of Liverpool, Liverpool, UK.
University of Liverpool · GBUniversity of Copenhagen · DK

Funding

Medical Research Council G0802448Medical Research Council MR/P008577/1Wellcome Trust 200335/Z/15/Z
6 · The paper itself

Abstract

backgroundReducing inequalities in adolescent mental health is a public health priority, yet the pathways that link social conditions to mental health outcomes in the early years are unclear. We aimed to evaluate the extent to which early years risk factors explain social inequalities in adolescent mental health in the UK.

methodsWe analysed data from 6509 children captured in the UK Millennium Cohort Study. Mental health was assessed through the socioemotional behavioural problems at age 14 (Strengths and Difficulties Questionnaire). The main exposure was maternal education at birth, used as a measure of childhood socioeconomic conditions (SECs), and used to calculate the relative index of inequality. Using causal mediation analysis, we assessed how perinatal, individual child, family, peer relation and neighbourhood-level factors measured up to age 3-mediated the total effect (TE) of SECs on adolescent socioemotional behavioural problems, estimating the proportion mediated and natural indirect effect (NIE) via each block of mediators, and all mediators together.

resultsChildren of mothers with no qualification were almost four times as likely to have socioemotional behavioural problems compared with degree plus level (relative risk (RR) 3.82, 95% CI 2.48 to 5.88). Overall, 63.9% (95% CI 50.2% to 77.6%) (NIE RR 1.97, 95% CI 1.63 to 2.37) of the TE (RR 4.40, 95% CI 3.18 to 6.07) of social inequalities on risk of adolescent socioemotional behavioural problems was mediated by early-life factors.

conclusionsAbout two-thirds of the social inequality in adolescent mental health was explained by early risk factors measured by age 3, highlighting the importance of public health interventions in this period.

Indexed as

Social ClassSocial Determinants of HealthAdolescent HealthCohort StudiesFemaleHumansMaleMental DisordersMental HealthPregnancyPrenatal Exposure Delayed EffectsResidence CharacteristicsSocioeconomic FactorsUnited KingdomEPIDEMIOLOGYLifecourse / Childhood CircumstancesMENTAL HEALTHSOCIAL INEQUALITIES

Identifiers

PMID31492761
PMCPMC6877708
OpenAlexW2972135530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.