Evidence map›Paper›PMID 31492755›Full record

ArticleThe Journal of biological chemistry2019

Differential modulation of energy landscapes of cyclic AMP receptor protein (CRP) as a regulatory mechanism for class II CRP-dependent promoters.

Wilfredo Evangelista, Aichun Dong, Mark A White, Jianquan Li, J Ching Lee

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wilfredo EvangelistaDepartment of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-1055.
Aichun DongDepartment of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-1055.
Mark A WhiteDepartment of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-1055.ORCID 0000-0003-1057-4203
Jianquan LiDepartment of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-1055.
J Ching LeeDepartment of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-1055 jclee@utmb.edu.
The University of Texas Medical Branch at Galveston · US

Funding

Role of Protein Dynamics in Modulating the Thermodynamic Linkages in AllosteryR01GM077551 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI LEE, JAMES C · 2006 to 2009
$1.4M
NIGMS NIH HHS R01 GM077551
6 · The paper itself

Abstract

The

Indexed as

Promoter Regions, GeneticBinding SitesCyclic AMP Receptor ProteinDimerizationEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialProtein DomainsProtein Subunitscrp protein, E coliCyclic AMP Receptor ProteinEscherichia coli ProteinsProtein Subunitsallosteric regulationbacterial signal transductionbacterial transcriptionenergy landscapeslong-range communicationRNA polymerasesignaling pathwaythermodynamicstranscription factortranscription regulation

Identifiers

PMID31492755
PMCPMC6802525
OpenAlexW2971931116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.