Evidence map›Paper›PMID 31492732›Full record

ArticleBMJ case reports2019

Atypical presentation of oncocytic parathyroid adenoma masquerading as metastatic carcinoma.

Suha Abdulla, Eamon Shamil, Mark Wilsher, Antony Jacob

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Suha AbdullaSchool of Medical Education, King's College London, London, UK.ORCID http://orcid.org/0000-0002-4443-7736
Eamon ShamilDepartment of ENT Surgery, University Hospital Lewisham, London, UK.
Mark WilsherDepartment of Pathology, University Hospital Lewisham, London, UK.
Antony JacobDepartment of ENT Surgery, University Hospital Lewisham, London, UK.
University Hospital Lewisham · GBKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid carcinoma is the rarest endocrine malignancy. Definitive diagnosis is challenging as it is difficult to distinguish malignant from benign disease. A 71-year-old man presented with weight loss and hypercalcaemia. CT scans revealed multiple lung nodules and lytic bone lesions that were consistent with metastatic dissemination. Technetium-99m-sestamibi-single-photon emission computed tomography scan showed an abnormal uptake in the right thyroid lobe. Fine-needle aspiration (FNA) was performed on three occasions. The patient underwent parathyroidectomy with ipsilateral hemithyroidectomy without postoperative complications. Microscopic examination showed a parathyroid neoplasm with fibrosis and intravascular tumour on a background of unremarkable thyroid parenchyma. This resulted in an initial impression of parathyroid carcinoma. Further review by two independent pathologists provided a final diagnosis of oncocytic parathyroid adenoma. This case highlights the subjectivity and interobserver variation with endocrine histological examination. FNA can induce changes that mimic parathyroid carcinoma on histology. An index of suspicion for benign parathyroid adenomas should be maintained.

Indexed as

Adenoma, OxyphilicAgedBiopsy, Fine-NeedleCarcinomaDiagnosis, DifferentialHumansHyperparathyroidism, PrimaryLung NeoplasmsMaleMultiple Pulmonary NodulesNeck DissectionNeoplasm MetastasisParathyroidectomyParathyroid NeoplasmsRadiopharmaceuticalsTechnetium Tc 99m SestamibiRadiopharmaceuticalsTechnetium Tc 99m Sestamibicarcinomafine needle aspirationhyperparathyroidismmetastasisParathyroid adenoma

Identifiers

PMID31492732
PMCPMC6731824
OpenAlexW2971940307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.