Evidence map›Paper›PMID 31492703›Full record

ArticleHeart (British Cardiac Society)2020

Guideline-directed therapy at discharge in patients with heart failure and atrial fibrillation.

Min-Soo Ahn, Byung Su Yoo, Junghan Yoon, Seung-Hwan Lee, Jang Young Kim, Sung Gyun Ahn, Young Jin Youn, Jun-Won Lee, Jung-Woo Son, Hye Sim Kim and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Heart (British Cardiac Society), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Design and deployment of the STEEER-AF trial to evaluate and improve guideline adherence: a cluster-randomized trial by the European Society of Cardiology and European Heart Rhythm Association.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  4. Advancing Guideline-Directed Medical Therapy in Heart Failure: Overcoming Challenges and Maximizing Benefits.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Min-Soo AhnDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0001-7896-8175
Byung Su YooDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea yubs@yonsei.ac.kr.ORCID 0000-0002-3395-4279
Junghan YoonDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-3363-2675
Seung-Hwan LeeDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-1186-0917
Jang Young KimDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-0813-7082
Sung Gyun AhnDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-1528-2739
Young Jin YounDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0001-7066-7474
Jun-Won LeeDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0001-6206-1704
Jung-Woo SonDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-1790-3228
Hye Sim KimCenter of Biomedical Data Science, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-7431-9722
Dae Ryong KangCenter of Biomedical Data Science, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-8792-9730
Hyun-Jai ChoDivision of Cardiology, Department of Internal Medicine/Cardiovascular Center, Seoul National University Hospital, Jongno-gu, Seoul, Republic of Korea.ORCID 0000-0002-2779-4037
Hae-Young LeeDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Republic of Korea.ORCID 0000-0002-9521-4102
Eun Seok JeonDivision of Cardiology, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-9946-5611
Seok-Min KangDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University Wonju College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-9856-9227
Dong-Ju ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.ORCID 0000-0003-0146-2189
Myeong-Chan ChoChungbuk National University Hospital, Chungju-si, Republic of Korea.ORCID 0000-0002-0047-0227
Yonsei University · KRSeoul National University Hospital · KRChungbuk National University Hospital · KRSeoul National University Bundang Hospital · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study evaluated the relationship between guideline adherence for recommended therapy on discharge and relevant 60-day and 1-year clinical outcomes in patients with acute heart failure (HF) with reduced ejection fraction and atrial fibrillation (AF).

methodsOf 5625 acute patients with HF in the Korean Acute Heart Failure registry, 986 patients with HF and documented AF were analysed. Guideline adherence scores were calculated for the prescription of ACE inhibitors, angiotensin receptor blockers, β-blockers, mineralocorticoid receptor antagonists and anticoagulants.

resultsIn patients with HF with AF, there was a significant trend of reduced 60-day and 1-year mortality rates and the composite end point with guideline adherence. According to the Cox proportion hazard model, poor adherence was associated with a significantly higher risk of 60-day mortality (HR 4.75; 95% CI 1.77 to 12.74) and the composite end point (HR 2.36; 95% CI 1.33 to 4.18) compared with good adherence. Furthermore, poor adherence was associated with a significantly higher risk of 1-year mortality compared with moderate (HR 1.64; 95% CI 1.15 to 2.33) and good adherence (HR 2.34; 95% CI 1.39 to 3.97) and with a higher risk of the 1-year composite end point compared with good adherence (HR 1.58; 95% CI 1.07 to 2.33).

conclusionBetter adherence to guidelines was associated with better 60-day and 1-year prognoses in patients with HF with AF.

Indexed as

MortalityPractice Guidelines as TopicAdrenergic beta-AntagonistsAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAnticoagulantsAtrial FibrillationFemaleGuideline AdherenceHeart FailureHumansMaleMiddle AgedMineralocorticoid Receptor AntagonistsAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAnticoagulantsMineralocorticoid Receptor Antagonistsatrial fibrillationheart failuremedication adherence

Identifiers

PMID31492703
PMCPMC7027027
OpenAlexW2972012120

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.