Evidence map›Paper›PMID 31492670›Full record

ArticleApplied and environmental microbiology2019

Hybrid Two-Component Sensors for Identification of Bacterial Chemoreceptor Function.

Rita A Luu, Rebecca A Schomer, Ceanne N Brunton, Richard Truong, Albert P Ta, Watumesa A Tan, Juanito V Parales, Yu-Jing Wang, Yu-Wen Huo, Shuang-Jiang Liu and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Insights into Chemoreceptor MCP2201-Sensing D-Malate.International journal of molecular sciences · 2025
    Article
  4. Identification of a dCache-type chemoreceptor inFrontiers in microbiology · 2024
    Article
  5. Review
  6. Discovery of a New Chemoeffector forACS bio & med chem Au · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Rita A LuuDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Rebecca A SchomerDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Ceanne N BruntonDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Richard TruongDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Albert P TaDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Watumesa A TanDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Juanito V ParalesDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Yu-Jing WangState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Yu-Wen HuoState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Shuang-Jiang LiuState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Jayna L DittyDepartment of Biology, College of Arts and Sciences, University of St. Thomas, St. Paul, Minnesota, USA.
Valley StewartDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA.
Rebecca E ParalesDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, Davis, California, USA reparales@ucdavis.edu.
University of California, Davis · USChinese Academy of Sciences · CNUniversity of St. Thomas - Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soil bacteria adapt to diverse and rapidly changing environmental conditions by sensing and responding to environmental cues using a variety of sensory systems. Two-component systems are a widespread type of signal transduction system present in all three domains of life and typically are comprised of a sensor kinase and a response regulator. Many two-component systems function by regulating gene expression in response to environmental stimuli. The bacterial chemotaxis system is a modified two-component system with additional protein components and a response that, rather than regulating gene expression, involves behavioral adaptation and results in net movement toward or away from a chemical stimulus. Soil bacteria generally have 20 to 40 or more chemoreceptors encoded in their genomes. To simplify the identification of chemoeffectors (ligands) sensed by bacterial chemoreceptors, we constructed hybrid sensor proteins by fusing the sensor domains of

Indexed as

Signal TransductionBacterial ProteinsChemotaxisEscherichia coliEscherichia coli ProteinsGene ExpressionGenome, BacterialMethyl-Accepting Chemotaxis ProteinsPseudomonas putidaBacterial ProteinsEscherichia coli ProteinsMethyl-Accepting Chemotaxis Proteinsbiosensormethyl-accepting chemotaxis proteinPseudomonas putidareceptortwo-component system

Identifiers

PMID31492670
PMCPMC6821969
OpenAlexW2971434367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.