ArticleParasites & vectors2019
Epidemiological distribution of genotypes of Giardia duodenalis in humans in Spain.
Article in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global prevalence of Giardia infection in nonhuman mammalian hosts: A systematic review and meta-analysis of five million animals.PLoS neglected tropical diseases · 2025Pooled it
- Genotyping and distribution ofParasitology · 2026Article
- Associations between Blastocystis spp., Campylobacter spp., Giardia duodenalis and Dientamoeba fragilis using Bayesian priors to account for diagnostic test accuracy.European journal of microbiology & immunology · 2025Article
- Prevalence and Genotyping of Water- and Food-Borne Parasitic Protozoans (Microorganisms · 2024Article
- Genotyping and epidemiological distribution of diarrhea-causing isolates of Giardia duodenalis in southeastern part of West Bengal, India.Parasitology research · 2023Article
- Genotyping ofArchives of Razi Institute · 2023Article
- The Gut-Wrenching Effects of Cryptosporidiosis and Giardiasis in Children.Microorganisms · 2023Review
- Assessment of the Health Status of Spanish Schoolchildren Based on Nutrimetry, Lifestyle and Intestinal Parasites.Nutrients · 2023Article
- Global molecular prevalence ofHeliyon · 2023Review
- First report of prevalence and assemblage analysis of Giardia duodenalis in pigs from Guangxi Zhuang Autonomous Region, southern China.Parasite (Paris, France) · 2023Article
- The detection and phylogenetic characterization ofFrontiers in cellular and infection microbiology · 2023Article
- Association Between Giardia Genotype and Oxidative Stress Biomarkers Among Giardia-Infected Children: A Case-Control Study.Acta parasitologica · 2022Article
- A scoping review of risk factors and transmission routes associated with human giardiasis outbreaks in high-income settings.Current research in parasitology & vector-borne diseases · 2022Article
- Detection of enteric parasites and molecular characterization ofParasitology · 2021Article
- One Health Approach to Zoonotic Parasites: Molecular Detection of Intestinal Protozoans in an Urban Population of Norway Rats,Pathogens (Basel, Switzerland) · 2021Article
- Multilocus Genotyping ofPathogens (Basel, Switzerland) · 2021Article
- Genetic Diversity and Prevalence ofFrontiers in cellular and infection microbiology · 2021Article
- The controversies surroundingCurrent research in parasitology & vector-borne diseases · 2021Review
- Molecular diversity of Giardia duodenalis in children under 5 years from the Manhiça district, Southern Mozambique enrolled in a matched case-control study on the aetiology of diarrhoea.PLoS neglected tropical diseases · 2021Article
- First multilocus sequence typing (MLST) of Giardia duodenalis isolates from humans in Romania.Parasites & vectors · 2020Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundAlthough the distribution of Giardia duodenalis genotypes in humans has been increasingly reported in recent years, data on possible differences in pathogen transmission between age groups and virulence between genotypes are scarce. The purpose of this study is to investigate the genetic diversity of G. duodenalis in humans in Spain and compare the distribution of G. duodenalis assemblages A and B between children and adults and clinical presentations between the two genotypes.
methodsIn the present study, 125 microscopy-positive fecal samples were collected from humans in Spain over a 7-year period. PCR and sequence analyses of the triosephosphate isomerase, β-giardin and glutamate dehydrogenase genes were used to identify the multilocus genotypes of G. duodenalis.
resultsSequence analysis of three genetic loci identified both G. duodenalis assemblages A (29) and B (66), with co-infections of the two in two patients. Among the sequences obtained in this study, four multilocus genotypes (MLGs) of the sub-assemblage AII were observed within assemblage A. In contrast, 19 MLGs were detected within assemblage B due to the high sequence diversity at each locus. One MLG, however, was found in 51.9% (27/52) of assemblage B samples. Children were more commonly infected by assemblage B (44/53 or 83%) than adults (22/42 or 52.4%; χ
conclusionsThese results illustrate the existence of differences in genotype distribution between children and adults and clinical presentations between G. duodenalis genotypes. They are useful in understanding the transmission of G. duodenalis in humans in Spain.
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