Evidence map›Paper›PMID 31492008›Full record

ArticleJournal of clinical medicine2019

The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging.

Vittorio Pirani, Paolo Pelliccioni, Serena De Turris, Alessandro Rosati, Alessandro Franceschi, Claudia Cesari, Michele Nicolai, Cesare Mariotti

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. State-of-the-Art Review: Ocular Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
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  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Vittorio PiraniEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy. piranivittorio@virgilio.it.
Paolo PelliccioniEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy. paopel@hotmail.it.
Serena De TurrisEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy. serena_deturris@hotmail.it.
Alessandro RosatiEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy. alessandro.rosati8@gmail.com.
Alessandro FranceschiEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy. a.franceschi.md@gmail.com.
Claudia CesariEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy. claclu@libero.it.
Michele NicolaiEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy. michele.nicolai@hotmail.it.
Cesare MariottiEye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy.
Marche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provided by the ophthalmologist, through clinical evaluation and with the aid of a multimodal imaging examination.

methodsWe hereby describe selected cases who came to our attention and were visited in our eye clinic. In all clinics, the use of retinal and optic disc multimodal imaging during ophthalmological evaluation allowed to make a diagnosis of an infectious disease.

resultsIn our tertiary referral center more than 60 patients with syphilis, tuberculosis and toxoplasmosis have been evaluated in the last two years: In 60% of cases the ophthalmological evaluation was secondary to a previous diagnosis of an infectious disease, while in the remaining cases the ophthalmologist, with the help of a multimodal imaging examination and clinical evaluation, represented the physician who leads to the diagnosis.

conclusionOur results confirm how in these life-threatening pathologies a prompt diagnosis is mandatory and may benefit from a multidisciplinary and multimodal imaging approach, especially during ophthalmological evaluation.

Indexed as

fluorescein angiographyfundus autofluorescenceindocyanine green angiographyinfectious uveitisoptical coherence tomographyoptical coherence tomography angiographysyphilistoxoplasmosistuberculosis

Identifiers

PMID31492008
PMCPMC6780210
OpenAlexW2972300713

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.