ArticleNeurobiology of aging2019
Neural evidence for age-related differences in representational quality and strategic retrieval processes.
Article in Neurobiology of aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- The endocannabinoid system and the ageing brain.Nature reviews. Neuroscience · 2026Review
- Aging shifts hippocampal reactivation from selective reinstatement to category-level misbinding during episodic memory.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Neural correlates and reinstatement of recent and remote memory in children and young adults.eLife · 2025Article
- Dedifferentiation of caudate functional organization is linked to reduced D1 dopamine receptor availability and poorer memory function in aging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Mnemonic But Not Contextual Feedback Signals Defy Dedifferentiation in the Aging Early Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Dissociative Effects of Age on Neural Differentiation at the Category and Item Levels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Demands on perceptual and mnemonic fidelity are a key determinant of age-related cognitive decline throughout the lifespan.Journal of experimental psychology. General · 2024Article
- Effects of Aging on Successful Object Encoding: Enhanced Semantic Representations Compensate for Impaired Visual Representations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Age-Related Changes to Multisensory Integration and Audiovisual Speech Perception.Brain sciences · 2023Review
- I remember it like it was yesterday: Age-related differences in the subjective experience of remembering.Psychonomic bulletin & review · 2022Review
- Understanding associative false memories in aging using multivariate analyses.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022Article
- Age-related neural dedifferentiation for individual stimuli: an across-participant pattern similarity analysis.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022Article
- Age-related declines in neural distinctiveness correlate across brain areas and result from both decreased reliability and increased confusability.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022Article
- Divided attention at retrieval does not influence neural correlates of recollection in young or older adults.NeuroImage · 2022Article
- Age-Dependent Contribution of Domain-General Networks to Semantic Cognition.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Age Effects on Neural Discriminability and Monitoring Process During Memory Retrieval for Auditory Words.Frontiers in aging neuroscience · 2022Article
- Age-related dedifferentiation and hyperdifferentiation of perceptual and mnemonic representations.Neurobiology of aging · 2021Article
- Greater Neural Differentiation in the Ventral Visual Cortex Is Associated with Youthful Memory in Superaging.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Tracking Age Differences in Neural Distinctiveness across Representational Levels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Executive function and high ambiguity perceptual discrimination contribute to individual differences in mnemonic discrimination in older adults.Cognition · 2021Article
Corrections and comments
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3 authors.
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Abstract
Mounting behavioral evidence suggests that declines in both representational quality and controlled retrieval processes contribute to episodic memory decline with age. The present study sought neural evidence for age-related change in these factors by measuring neural differentiation during encoding of paired associates and changes in regional blood oxygenation level-dependent activity and functional connectivity during retrieval conditions that placed low (intact pairs) and high (recombined pairs) demands on controlled retrieval processes. Pattern similarity analysis revealed age-related declines in the differentiation of stimulus representations at encoding, manifesting as both reduced pattern similarity between closely related events and increased pattern similarity between distinct events. During retrieval, both groups increased recruitment of areas within the core recollection network when endorsing studied pairs, including the hippocampus and angular gyrus. In contrast, only younger adults increased recruitment of, and hippocampal connectivity with, lateral prefrontal regions during correct rejections of recombined pairs. These results provide evidence for age-related changes in representational quality and in the neural mechanisms supporting memory retrieval under conditions of high, but not low, control demand.
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