Evidence map›Paper›PMID 31491537›Full record

Trial reportAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2019

Effect of cysteinyl leukotriene receptor 1 blockade on aeroallergen-induced nasal recruitment of CD49d expressing neutrophils.

Lisa M Sammon, Syed-Rehan A Hussain, Melinda Smith, Michelle Rohlfing, Jennifer L Santoro, Mitchell H Grayson

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03039101 (Double Blind Study of Leukotriene Antagonism in the Nasal Recruitment of CD49d Expressing Neutrophils in Atopic Subjects), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03039101 nacompletednot on this map

Double Blind Study of Leukotriene Antagonism in the Nasal Recruitment of CD49d Expressing Neutrophils in Atopic Subjects

TypeinterventionalSponsorMitchell GraysonRan2017 to 2018Enrolled25ConditionsNasal AllergyArmsNasal lavage, Nasal allergen challenge, Epicutaneous skin testing, Peripheral blood, Montelukast 10Mg Tablet
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lisa M SammonDivision of Allergy and Immunology, Department of Pediatrics Nationwide Children's Hospital and The Ohio State University Columbus, Ohio.
Syed-Rehan A HussainDivision of Allergy and Immunology, Department of Pediatrics Nationwide Children's Hospital and The Ohio State University Columbus, Ohio; Center for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Melinda SmithDivision of Clinical Research, Nationwide Children's Hospital Columbus, Ohio.
Michelle RohlfingDivision of Allergy and Immunology, Department of Pediatrics Nationwide Children's Hospital and The Ohio State University Columbus, Ohio; Center for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Jennifer L SantoroDivision of Allergy and Immunology, Department of Pediatrics Nationwide Children's Hospital and The Ohio State University Columbus, Ohio; Center for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Mitchell H GraysonDivision of Allergy and Immunology, Department of Pediatrics Nationwide Children's Hospital and The Ohio State University Columbus, Ohio; Center for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio. Electronic address: wheeze@allergist.com.

Funding

Mechanisms of Atopic Disease Development in the LungR01HL087778 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI GRAYSON, MITCHELL H · 2008 to 2018
$3.7M
NHLBI NIH HHS R01 HL087778
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetatesAdultAir PollutantsAllergensAnimalsCyclopropanesDouble-Blind MethodFemaleHumansHypersensitivityIntegrin alpha4Leukotriene AntagonistsMaleMiceMiddle AgedNasal Lavage FluidAcetatesAir PollutantsAllergensCyclopropanesIntegrin alpha4Leukotriene Antagonistsleukotriene D4 receptormontelukastQuinolinesReceptors, LeukotrieneSulfides

Identifiers

PMID31491537
PMCPMC6825584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.