Evidence map›Paper›PMID 31491336›Full record

ArticleGenome2019

Molecular epidemiology of carbapenem-resistance plasmids using publicly available sequences.

Galen E Card, Brandon D Pickett, Perry G Ridge, Richard A Robison

Open access · greenAbstract read
In one paragraph

Article in Genome, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Galen E CardDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.
Brandon D PickettDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.
Perry G RidgeDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.
Richard A RobisonDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.
Brigham Young University · US

Funding

Multiplexed, Non-Amplified, Nucleic Acid-Based Identification of Multidrug Resistant Pathogens Using an Integrated Optofluidic PlatformR01AI116989 · NIAID · BRIGHAM YOUNG UNIVERSITY · PI HAWKINS, AARON R., PITT, WILLIAM G · 2015 to 2019
$5.4M
NIAID NIH HHS R01 AI116989
6 · The paper itself

Abstract

Carbapenem-resistant bacteria have quickly become a worldwide concern in nosocomial infections. Of the seven known carbapenemases, four have been shown to be particularly problematic: KPC, NDM, IMP, and VIM. To date, many local and species- or carbapenemase-specific epidemiological studies have been performed, which often focus on the organism itself. This report attempts to perform an inclusive (encompass both species and carbapenemase) epidemiologic study using publicly available plasmid sequences from NCBI. In this report, the gene content of these various plasmids has been characterized, replicon types of the plasmids identified, and the global spread and species promiscuity of the plasmids analyzed. Additionally, support to several groups targeting plasmid maintenance and transfer mechanisms to slow the spread of resistance plasmids is given.

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCarbapenemsChinaDatabases, Nucleic AcidDrug Resistance, BacterialPlasmidsRepliconUnited StatesAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsantibiotic resistancecarbapenemasecarbapénémasedistribution mondialeEnterobacteriaceaeglobal distributionplasmidplasmiderésistance aux antimicrobiens

Identifiers

PMID31491336
PMCPMC9221968
OpenAlexW2971458712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.