Evidence map›Paper›PMID 31491073›Full record

ArticleThe New England journal of medicine2019

Pulmonary Lipid-Laden Macrophages and Vaping.

Sean D Maddock, Meghan M Cirulis, Sean J Callahan, Lynn M Keenan, Cheryl S Pirozzi, Sanjeev M Raman, Scott K Aberegg

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in The New England journal of medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04616313 (Novel Pulmonary Imaging of Lung Structure and Function in Symptomatic and Asymptomatic E-cigarette Smokers), which is not on this map. Cited by 108 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04616313 recruitingnot on this mapstarted 2023, after this paper: background citation

Novel Pulmonary Imaging of Lung Structure and Function in Symptomatic and Asymptomatic E-cigarette Smokers

TypeobservationalSponsorWestern University, CanadaRan2023 to 2027Enrolled150ConditionsE Cigarette UseArmsHyperpolarized Xenon-129 MRI of the lungs, Computed Tomography (CT), Pulmonary Function Tests (PFT), Cardiopulmonary exercise testing (CPET), Sputum analysis
3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Literature Review of E-Cigarette-Related Illness and Injury: Not Just for the Respirologist.International journal of environmental research and public health · 2020
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. E-Cigarette or Vaping Product Use-Associated Lung Injury: A Comprehensive Review.International journal of environmental research and public health · 2025
    Review
  9. Review
  10. La Tunisie medicale · 2025
    Article
  11. Vaping-associated illness: a reassessment.International journal of emergency medicine · 2024
    Article
  12. Respiratory management of acute chest syndrome in children with sickle cell disease.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  13. Article
  14. Macrophage Dysfunction in Respiratory Disease.Results and problems in cell differentiation · 2024
    Review
  15. Article
  16. E-cigarette use-associated lung injury (EVALI).Pneumologie (Stuttgart, Germany) · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Article

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Sean D MaddockUniversity of Utah Health, Salt Lake City, UT sean.callahan@hsc.utah.edu.ORCID 0000-0002-0242-9551
Meghan M CirulisUniversity of Utah Health, Salt Lake City, UT sean.callahan@hsc.utah.edu.
Sean J CallahanUniversity of Utah Health, Salt Lake City, UT sean.callahan@hsc.utah.edu.
Lynn M KeenanUniversity of Utah Health, Salt Lake City, UT sean.callahan@hsc.utah.edu.
Cheryl S PirozziUniversity of Utah Health, Salt Lake City, UT sean.callahan@hsc.utah.edu.
Sanjeev M RamanUniversity of Utah Health, Salt Lake City, UT sean.callahan@hsc.utah.edu.
Scott K AbereggUniversity of Utah Health, Salt Lake City, UT sean.callahan@hsc.utah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Electronic Nicotine Delivery SystemsVapingIllinoisLipidsMacrophagesMacrophages, AlveolarWisconsinLipids

Identifiers

PMID31491073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.