Evidence map›Paper›PMID 31490986›Full record

ArticlePloS one2019

What are the characteristics that lead physicians to perceive an ICU stay as non-beneficial for the patient?

Jean-Pierre Quenot, Audrey Large, Nicolas Meunier-Beillard, Paul-Simon Pugliesi, Pamina Rollet, Amaury Toitot, Pascal Andreu, Hervé Devilliers, Antoine Marchalot, Fiona Ecarnot and 3 more

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. End-of-life practices in 11 German intensive care units : Results from the ETHICUS-2 study.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jean-Pierre QuenotDepartment of Intensive Care, François Mitterrand, University Hospital, Dijon, France.ORCID 0000-0003-2351-682X
Audrey LargeDepartment of Intensive Care, François Mitterrand, University Hospital, Dijon, France.
Nicolas Meunier-BeillardINSERM CIC 1432, Clinical Epidemiology, University of Burgundy, Dijon, France.
Paul-Simon PugliesiDepartment of Intensive Care, William Morey Hospital, Chalon sur Saône, France.ORCID 0000-0002-9270-1861
Pamina RolletDepartment of Intensive Care, Nord Franche-Comté Hospital, Trevenans, France.
Amaury ToitotDepartment of Intensive Care, Nord Franche-Comté Hospital, Trevenans, France.
Pascal AndreuDepartment of Intensive Care, François Mitterrand, University Hospital, Dijon, France.
Hervé DevilliersINSERM CIC 1432, Clinical Epidemiology, University of Burgundy, Dijon, France.
Antoine MarchalotDepartment of Intensive Care, Dieppe General Hospital, Dieppe, France.
Fiona EcarnotEA3920, Department of Cardiology, University Hospital Besancon, France.
Auguste DargentDepartment of Intensive Care, François Mitterrand, University Hospital, Dijon, France.
Jean-Philippe RigaudDepartment of Intensive Care, Dieppe General Hospital, Dieppe, France.
INSTINCT study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe sought to describe the characteristics that lead physicians to perceive a stay in the intensive care unit (ICU) as being non-beneficial for the patient. MATERIALS AND

methodsIn the first step, we used a multidisciplinary focus group to define the characteristics that lead physicians to consider a stay in the ICU as non-beneficial for the patient. In the second step, we assessed the proportion of admissions that would be perceived by the ICU physicians as non-beneficial for the patient according to our focus group's definition, in a large population of ICU admissions in 4 French ICUs over a period of 4 months.

resultsAmong 1075 patients admitted to participating ICUs during the study period, 155 stays were considered non-beneficial for the patient, yielding a frequency of 14.4% [95% confidence interval (CI) 8.9, 19.9]. Average age of these patients was 72 ±12.8 years. Mortality was 43.2% in-ICU [95%CI 35.4, 51.0], 55% [95%CI 47.2, 62.8] in-hospital. The criteria retained by the focus group to define a non-beneficial ICU stay were: patient refusal of ICU care (23.2% [95%CI 16.5, 29.8]), and referring physician's desire not to have the patient admitted (11.6% [95%CI 6.6, 16.6]). The characteristics that led physicians to perceive the stay as non-beneficial were: patient's age (36.8% [95%CI 29.2, 44.4]), unlikelihood of recovering autonomy (61.9% [95%CI 54.3, 69.6]), prior poor quality of life (60% [95%CI 52.3, 67.7]), terminal status of chronic disease (56.1% [95%CI 48.3, 63.9]), and all therapeutic options have been exhausted (35.5% [95%CI 27.9, 43.0]). Factors that explained admission to the ICU of patients whose stay was subsequently judged to be non-beneficial included: lack of knowledge of patient's wishes (52% [95%CI 44.1, 59.9]); decisional incapacity (sedation) (69.7% [95%CI 62.5, 76.9]); inability to contact family (34% [95%CI 26.5, 41.5]); pressure to admit (from family or other physicians) (50.3% [95%CI 42.4, 58.2]).

conclusionsNon-beneficial ICU stays are frequent. ICU admissions need to be anticipated, so that patients who would yield greater benefit from other care pathways can be correctly oriented in a timely manner.

Indexed as

Health Knowledge, Attitudes, PracticeAdultFemaleHumansIntensive Care UnitsLength of StayMalePatient AdmissionPhysiciansSurveys and Questionnaires

Identifiers

PMID31490986
PMCPMC6730882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.