Evidence map›Paper›PMID 31490968›Full record

ArticlePloS one2019

How could an African swine fever outbreak evolve in an enzootic context? The case of Imerintsiatosika, Madagascar in 2015.

Harentsoaniaina Rasamoelina Andriamanivo, Dinaniaina Randriamananjara, Rijaniaina Ambinintsoa Ralalarison, Lalaina Arivony Nomenjanahary, Nivohanitra Perle Razafindraibe, Edithe Diana Andria-Mananjara, Domoina Oninirina Rakotomanana, Peter Samuel Fenozara, Marcellin Biarmann, Ariane Halm and 3 more

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Harentsoaniaina Rasamoelina AndriamanivoEpidemic Intelligence Unit, SEGA One Health Network, Indian Ocean Commission, Ébène, Mauritius.ORCID 0000-0003-4418-3358
Dinaniaina RandriamananjaraDépartement Vétérinaire, Faculté de Médecine d'Antananarivo, Antananarivo, Madagascar.
Rijaniaina Ambinintsoa RalalarisonCabinet Vétérinaire, Imerintsiatosika, Arivonimamo, Madagascar.
Lalaina Arivony NomenjanaharyVirology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Nivohanitra Perle RazafindraibeIndian Ocean Field Epidemiology Training Programme, SEGA One Health, Network, Indian Ocean Commission, Ébène, Mauritius.
Edithe Diana Andria-MananjaraDépartement de Recherche Zootechnique, Vétérinaire et Piscicole), Antananarivo, Madagascar.
Domoina Oninirina RakotomananaDépartement de Recherche Zootechnique, Vétérinaire et Piscicole), Antananarivo, Madagascar.
Peter Samuel FenozaraDirection des Services Vétérinaires, Antananarivo, Madagascar.
Marcellin BiarmannDirection des Services Vétérinaires, Antananarivo, Madagascar.
Ariane HalmEpidemic Intelligence Unit, SEGA One Health Network, Indian Ocean Commission, Ébène, Mauritius.
Harimahefa RazafimandimbyEpidemic Intelligence Unit, SEGA One Health Network, Indian Ocean Commission, Ébène, Mauritius.
Loïc FlachetEpidemic Intelligence Unit, SEGA One Health Network, Indian Ocean Commission, Ébène, Mauritius.
Eric CardinaleEpidemic Intelligence Unit, SEGA One Health Network, Indian Ocean Commission, Ébène, Mauritius.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever (ASF) is a haemorrhagic contagious pig disease generally causing high mortality. ASF is enzootic in Madagascar with outbreaks reported each year. An ASF outbreak occurred in May 2015 in the municipality of Imerintsiatosika in Madagascar. We investigated the outbreak to describe it and to identify risk factors in order to propose control measures, and to document evidence of an ASF outbreak in an enzootic country. We took biological samples from very sick and dying pigs, sold by the farmer to the butcher, for PCR analysis. An active search for all possible farm-cases was carried out. A definition of suspected farm-case was established and we implemented a descriptive survey and a retrospective cohort study. Laboratory results confirmed ASF virus infection. Suspected farm-cases represented 81 farms out of 922. Out of 3081 pigs of infected farms, 44% (95% CI: 42-46%) were sick, of which 47% were sold or slaughtered. Case fatality was 60% (95% CI: 56-63%) while 21% (95% CI: 19-24%) of the diseased pigs recovered. The outbreak duration was nine months and half of the infected farms' pig population remained after the outbreak. Compared to the exotic breed, local pigs had twice the risk of infection. It is the first detailed report of an ASF outbreak in an enzootic situation. The disease still has a large impact with 50% animals lost. However, the case fatality is lower than expected that suggests the possibility of resistance and subclinical cases. Proximity to road and increased number of farms are risk factors so biosecurity measures are needed. Further studies are needed to understand why pigs of local breed are more affected. Finally, an acceptable alternative to the sale of sick animals should be found as this currently is the breeders' means to reducing economic loss.

Indexed as

African Swine FeverAnimalsDisease OutbreaksIncidenceMadagascarRisk FactorsSwine

Identifiers

PMID31490968
PMCPMC6730906

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.