Evidence map›Paper›PMID 31490685›Full record

ArticleJournal of natural products2019

Yangpumicins F and G, Enediyne Congeners from

Zilong Wang, Zhongqing Wen, Ling Liu, Xiangcheng Zhu, Ben Shen, Xiaohui Yan, Yanwen Duan, Yong Huang

Abstract read
In one paragraph

Article in Journal of natural products, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Microbial genomics · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Characterization of TnmH as anJournal of medicinal chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zilong WangXiangya International Academy of Translational Medicine at Central South University , Changsha , Hunan 410013 , People's Republic of China.
Zhongqing WenXiangya International Academy of Translational Medicine at Central South University , Changsha , Hunan 410013 , People's Republic of China.
Ling LiuXiangya International Academy of Translational Medicine at Central South University , Changsha , Hunan 410013 , People's Republic of China.
Xiangcheng ZhuXiangya International Academy of Translational Medicine at Central South University , Changsha , Hunan 410013 , People's Republic of China.
Xiaohui YanXiangya International Academy of Translational Medicine at Central South University , Changsha , Hunan 410013 , People's Republic of China.
Yanwen DuanXiangya International Academy of Translational Medicine at Central South University , Changsha , Hunan 410013 , People's Republic of China.
Yong HuangXiangya International Academy of Translational Medicine at Central South University , Changsha , Hunan 410013 , People's Republic of China.ORCID 0000-0002-3163-1716

Funding

Genome Mining for Enediyne Natural Products from ActinomycetalsR01GM115575 · NIGMS · SCRIPPS FLORIDA · PI SHEN, BEN · 2016 to 2019
$1.9M
NIGMS NIH HHS R01 GM115575
6 · The paper itself

Abstract

Enediyne natural products are among the most cytotoxic small molecules and thus excellent payload candidates for the development of antibody-drug conjugates (ADCs). Here we report the isolation and structural elucidation of two new 10-membered anthraquinone-fused enediynes, yangpumicins (YPM) F (

Indexed as

Anti-Bacterial AgentsCell Line, TumorDrug Screening Assays, AntitumorHumansMicrobial Sensitivity TestsMicromonosporaSpectrum AnalysisAnti-Bacterial Agents

Identifiers

PMID31490685
PMCPMC7170010

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.