Evidence map›Paper›PMID 31490676›Full record

ArticleAnalytical chemistry2019

Hybrid 193 nm Ultraviolet Photodissociation Mass Spectrometry Localizes Cardiolipin Unsaturations.

Luis A Macias, Clara L Feider, Livia S Eberlin, Jennifer S Brodbelt

Abstract read
In one paragraph

Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Dual Metal Electrolysis in Theta Capillary for Lipid Analysis.International journal of mass spectrometry · 2023
    Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis A MaciasDepartment of Chemistry , University of Texas , Austin , Texas 78712 , United States.
Clara L FeiderDepartment of Chemistry , University of Texas , Austin , Texas 78712 , United States.ORCID 0000-0003-3972-7533
Livia S EberlinDepartment of Chemistry , University of Texas , Austin , Texas 78712 , United States.ORCID 0000-0002-3885-3215
Jennifer S BrodbeltDepartment of Chemistry , University of Texas , Austin , Texas 78712 , United States.ORCID 0000-0003-3207-0217

Funding

UVPD-MS Characterization of LipopolysaccharidesR01GM103655 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI BRODBELT, JENNIFER S. · 2012 to 2019
$2.3M
Mass Spectrometry Imaging for Clinical Diagnosis and Prognosis of Human CancersR00CA190783 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI SCHIAVINATO EBERLIN, LIVIA · 2016 to 2018
$677k
NCI NIH HHS R00 CA190783NIGMS NIH HHS R01 GM103655
6 · The paper itself

Abstract

Developing alternative MS/MS strategies to distinguish isomeric lipids has become a high impact goal in shotgun lipidomics. Novel approaches have been developed to resolve structural features that are not discernible by traditional shotgun methods and have consequently promoted the discovery of new disease biomarkers. However, these methods have largely been limited to characterizing lipids with low structural complexity. Here, ultraviolet photodissociation (UVPD) strategies for phospholipid characterization are expanded for analysis of cardiolipins (CL), a class of phospholipids that exhibits a higher degree of structural complexity. A hybrid collision induced dissociation/193 nm UVPD (CID/UVPD) approach was implemented to pinpoint the location of both double bond and cyclopropyl unsaturations on the four acyl chains of CLs. This strategy was complemented with CID for the

Indexed as

Mass SpectrometryPhotochemical ProcessesUltraviolet RaysCardiolipinsCardiolipins

Identifiers

PMID31490676
PMCPMC6910719

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.