ArticleACS applied materials & interfaces2019
Electrochemically Controlled Dissolution of Nanocarbon-Cellulose Acetate Phthalate Microneedle Arrays.
Article in ACS applied materials & interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 41 citations in OpenAlex.
- The application prospect of microneedles for sports injuries: a narrative review.Annals of medicine · 2025Review
- Electrical Microneedles for Wound Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Progressive microneedles for targeting and intelligent drug delivery.Asian journal of pharmaceutical sciences · 2025Review
- A Bibliometric Analysis of Microneedle-Mediated Drug Delivery: Trends, Hotspots, and Future Directions.Drug design, development and therapy · 2025Review
- Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024Review
- Smart Responsive Microneedles for Controlled Drug Delivery.Molecules (Basel, Switzerland) · 2023Review
- Recent developments in natural biopolymer based drug delivery systems.RSC advances · 2023Review
- Ex Vivo Transdermal Delivery of Nicotinamide Mononucleotide Using Polyvinyl Alcohol Microneedles.Polymers · 2023Article
- Electrochemical Microneedles: Innovative Instruments in Health Care.Biosensors · 2022Review
- Detachable dissolvable microneedles: intra-epidermal and intradermal diffusion, effect on skin surface, and application in hyperpigmentation treatment.Scientific reports · 2021Article
- Microneedles in Drug Delivery: Progress and Challenges.Micromachines · 2021Review
- Smart Microneedles for Therapy and Diagnosis.Research (Washington, D.C.) · 2020Review
- Microneedle-Mediated Delivery of Extracellular Matrix-Inspired Peptides for Mitigation of Burn Wound Progression and Support of Tissue Repair.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transdermal microneedles have captured the attention of researchers in relation to a variety of applications, and silicone-based molds required to produce these systems are now widely available and can be readily manufactured on the lab bench. The production of nanocomposite microneedle arrays through micromolding techniques is described. The formulation of nanoparticulate carbon along with pH sensitive cellulose acetate phthalate as a polymeric binder is shown to produce conductive microneedles whose swelling/dissolution properties can be controlled electrochemically. Through exploiting hydrogen evolution at the microneedle array, changes in local pH can induce swelling within the needle structure and could lay the foundations for a new approach to the smart device controlled delivery of therapeutic agents. The surface modification of the carbon needles with palladium and cysteine is critically assessed from sensing and drug delivery perspectives.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.