ArticleJournal of veterinary internal medicine2019
Long-term survival of dogs treated for gallbladder mucocele by cholecystectomy, medical management, or both.
Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 54 citations in OpenAlex.
- Clinical and Nutritional Management of Gallbladder Mucocele in Dogs: A Four-Case Series.Animals : an open access journal from MDPI · 2026Article
- Beyond pneumoperitoneum: technical feasibility and predictive factors for gasless laparoscopic cholecystectomy in dogs.Veterinary research communications · 2026Article
- Ultrasonographic Gallbladder Findings and Bile Culture Results in Dogs with Extrahepatic Biliary Disorders: A Retrospective Exploratory Case Series.Life (Basel, Switzerland) · 2026Article
- Characteristics and outcomes of dogs undergoing cholecystectomy for diseases other than a mature gallbladder mucocele: a retrospective cohort study.Journal of veterinary internal medicine · 2026Article
- Evaluation of Hepatoprotectants in the Management of Subclinical Gallbladder Mucocele in Dogs.Animals : an open access journal from MDPI · 2025Article
- Choledochal Stenting for Treatment of Extrahepatic Biliary Obstruction in Dogs with Ruptured Gallbladder: 2 Cases.Veterinary sciences · 2025Article
- Intra-Operative Cholangiography With Indocyanine Green Used to Assess Bile Duct Patency in a Dog With a Ruptured Gallbladder Mucocele.Veterinary medicine and science · 2025Article
- Increased risk of gallbladder rupture and death in small-breed dogs with concurrent hypothyroidism or pancreatitis undergoing cholecystectomy for gallbladder mucoceles.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2025Article
- Clinical findings and prognostic factors for immediate survival in 33 dogs undergoing surgery for biliary peritonitis.Veterinary surgery : VS · 2025Article
- Magnetic Resonance Cholangiopancreatography for Cholangiopancreatic Duct Imaging in Dogs.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2025Article
- Nutritional Factors Related to Canine Gallbladder Diseases-A Scoping Review.Veterinary sciences · 2024Review
- MUC5AC and MUC5B expression in canine gallbladder mucocele epithelial cells.The Journal of veterinary medical science · 2023Article
- Surgical Management Of Feline Biliary Tract Disease: Decision-making and techniques.Journal of feline medicine and surgery · 2023Review
- Long-Term Outcome after Cholecystectomy without Common Bile Duct Catheterization and Flushing in Dogs.Animals : an open access journal from MDPI · 2022Article
- A multicenter retrospective study assessing progression of biliary sludge in dogs using ultrasonography.Journal of veterinary internal medicine · 2022Article
- Ultrasonographic patterns, clinical findings, and prognostic variables in dogs from Asia with gallbladder mucocele.Journal of veterinary internal medicine · 2022Article
- Extradural anaesthesia-analgesia in dogs undergoing cholecystectomy: A single centre retrospective study.Frontiers in veterinary science · 2022Article
- Evaluation of coagulation parameters in dogs with gallbladder mucoceles.Journal of veterinary internal medicine · 2021Article
- Article
- Long-term survival of dogs treated for gallbladder mucocele by cholecystectomy, medical management, or both.Journal of veterinary internal medicine · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGallbladder mucoceles (GBM) typically are treated by cholecystectomy. Medical management rarely has been reported and medical and surgical management have not been compared. HYPOTHESIS/
objectivesTo compare survival of dogs treated for GBM by medical management or cholecystectomy or both. ANIMALS: Eighty-nine client-owned dogs diagnosed with GBM that received cholecystectomy or medical treatment or both from 2011 to 2017.
methodsPotential cases were identified by searching the medical records database. Data collected included signalment, clinicopathologic results, treatments, and ultrasonographic images and reports. Dogs were grouped according to the treatment received (medical management, surgical treatment, or both) that was chosen at the discretion of the attending veterinarian. Survival analysis was performed and prognostic variables identified and compared between treatment groups.
resultsOf dogs surviving at least 14 days after diagnosis, median survival times were 1802 (95% confidence interval [CI], 855-not reached) days, 1340 (95% CI, 444-1340) days, and 203 (95% CI, 18-525) days, for the surgical, medical, and medical then surgical treatment groups, respectively, and differed significantly (P < .0001). Gallbladder mucocele type (P = .05), serum alkaline phosphatase activity (P = .0001), and serum creatinine (P = .002) and phosphorus (P = .04) concentrations were associated with decreased survival across groups. Suspicion of biliary rupture on abdominal ultrasound (AUS) examination was correlated with increased survival in the surgical group (P = .02). CONCLUSIONS AND CLINICAL IMPORTANCE: Cholecystectomy for the treatment of GBM results in the best long-term survival in dogs surviving the immediate postoperative period (14 days) compared to medical management. Although medical management is associated with shorter survival compared to surgical treatment, it is a reasonable alternative when surgery cannot be pursued.
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