Evidence map›Paper›PMID 31490011›Full record

ArticleClinical cardiology2019

Risk of ischemic stroke and utility of CHA

Maria Tomasdottir, Leif Friberg, Ziad Hijazi, Johan Lindbäck, Jonas Oldgren

Abstract readMulticenter Study
In one paragraph

Article in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Review
  6. Relationship between vascular calcification assessed by chest CT and CHAQuantitative imaging in medicine and surgery · 2026
    Article
  7. Thalassemia and hypercoagulability.Hematology. American Society of Hematology. Education Program · 2025
    Review
  8. Spotlight on the 2024 ESC/EACTS management of atrial fibrillation guidelines: 10 novel key aspects.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Review
  9. Article
  10. Refining the CHA2DS2VASc risk stratification scheme: shall we drop the sex category criterion?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  11. Left atrial appendage angiography for stroke risk prediction in patients with atrial fibrillation.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Management of atrial fibrillation: two decades of progress - a scientific statement from the European Cardiac Arrhythmia Society.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022
    Review
  16. Article
  17. Article
  18. Women and atrial fibrillation.Journal of cardiovascular electrophysiology · 2021
    Review
  19. Article
  20. Correlation Between CHAFrontiers in cardiovascular medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria TomasdottirDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0002-4981-2398
Leif FribergDepartment of Clinical Sciences at Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
Ziad HijaziDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Johan LindbäckUppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Jonas OldgrenDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe magnitude of increased risk of stroke in women with atrial fibrillation (AF) remains uncertain. HYPOTHESIS: We investigated the risk of ischemic stroke and death in women and men with AF, and the risk associated with individual non-sex CHA

methodsRetrospective cohort study of 231 077 (48.1% women) nonselected patients with AF not receiving oral anticoagulation from 2006 to 2014. Data from cross-linked national Swedish registers. The outcome was the first occurrence of ischemic stroke or death. Median age was 82 and 75 years in women and men, respectively. Mean follow-up was 2.5 years.

resultsHazard ratios, adjusted for non-sex CHA

conclusionsThe risk of ischemic stroke was 1.5-fold higher in women compared to men but this association appears to be the result of confounding by age. In the low risk end, the CHA

Indexed as

AgedAged, 80 and overAtrial FibrillationBrain IschemiaFemaleHumansIncidenceMalePrognosisRisk AssessmentRisk FactorsSeverity of Illness IndexSex DistributionSex FactorsSurvival RateSwedenatrial fibrillationCHA2DS2-VASc risk scoreischemic stroke

Identifiers

PMID31490011
PMCPMC6788468

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.