Evidence map›Paper›PMID 31489515›Full record

ReviewHeart failure reviews2020

Usefulness and clinical relevance of left ventricular global longitudinal systolic strain in patients with heart failure with preserved ejection fraction.

Carsten Tschöpe, Michele Senni

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04626375 phase4completednot on this map

Effects of L-arginine on Myocardial Energetic Efficiency and Global Longitudinal Strain

TypeinterventionalSponsorFederico II UniversityRan2020 to 2021Enrolled54ConditionsMyocardial DysfunctionArmsBioarginine, Placebo oral tablet
NCT07150455 completednot on this mapstarted 2025, after this paper: background citation

Evaluation of Myocardial Function by Global Longitudinal Strain (GLS) Measurement in 2D Echocardiographic Examination of Patients With Fibromyalgia

TypeobservationalSponsorAnkara Training and Research HospitalRan2025 to 2026Enrolled118ConditionsFibromyalgia (FM), Subclinical Ventricular Dysfunction, Myocardial FunctionArmsEchocardiographic Assessment (2D Speckle Tracking)
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carsten TschöpeDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum Augustenburgerplatz 1, 13353, Berlin, Germany. carsten.tschoepe@charite.de.
Michele SenniCardiology Division, Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, several studies have shown the usefulness and clinical relevance of left ventricular global longitudinal systolic strain (GLS) in different cardiovascular diseases. In line with this, the role of GLS in patients with heart failure with preserved ejection fraction (HFpEF) has achieved great importance in this predominant form of heart failure in the last years. In this regard, GLS has shown to be not only a sensitive parameter to detect subtle myocardial abnormalities but also a parameter of clinical and prognostic relevance in patients with HFpEF. In this review, we analyze the current evidence concerning the clinical relevance of GLS in patients with HFpEF and we discuss the potential usefulness of GLS in this complex and heterogeneous condition for which so far no effective therapy exists.

Indexed as

SystoleDisease ProgressionEchocardiographyHeart FailureHumansMyocardial IschemiaPrognosisStroke VolumeVentricular Dysfunction, LeftEchocardiographyGlobal longitudinal strainHeart failure

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.