Evidence map›Paper›PMID 31489183›Full record

ArticleJournal of global health2019

A cross-sectional survey of practices and knowledge among antibiotic retailers in Nairobi, Kenya.

Dishon Muloi, Eric M Fèvre, Judy Bettridge, Robert Rono, Daniel Ong'are, James M Hassell, Maurice K Karani, Patrick Muinde, Bram van Bunnik, Alice Street and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Dishon MuloiUsher Institute of Population Health Sciences & Informatics, University of Edinburgh, Edinburgh, UK.
Eric M FèvreInstitute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Judy BettridgeInstitute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Robert RonoInternational Livestock Research Institute, Nairobi, Kenya.
Daniel Ong'areInternational Livestock Research Institute, Nairobi, Kenya.
James M HassellInstitute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Maurice K KaraniInternational Livestock Research Institute, Nairobi, Kenya.
Patrick MuindeInternational Livestock Research Institute, Nairobi, Kenya.
Bram van BunnikUsher Institute of Population Health Sciences & Informatics, University of Edinburgh, Edinburgh, UK.
Alice StreetSocial Anthropology, School of Social and Political Science, University of Edinburgh, Edinburgh, UK.
Margo Chase-ToppingCentre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
Amy B PedersenInstitute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Melissa J WardCentre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
Mark WoolhouseUsher Institute of Population Health Sciences & Informatics, University of Edinburgh, Edinburgh, UK.
International Livestock Research Institute · KEUniversity of Edinburgh · GBCentre for Immunity, Infection and Evolution · GBUniversity of Liverpool · GBUniversity of Oxford · GB

Funding

Medical Research Council G1100783Medical Research Council MR/R000093/1Medical Research Council MR/R015090/1Wellcome Trust
6 · The paper itself

Abstract

backgroundAntimicrobial resistance (AMR) driven by antibiotic consumption is a growing global health threat. However, data on antimicrobial consumption patterns in low- and middle-income countries (LMICs) is sparse. Here, we investigate the patterns of antibiotic sales in humans and livestock in urban Nairobi, Kenya, and evaluate the level of awareness and common behaviours related to antibiotic use and AMR amongst human and veterinary pharmacists.

methodsA total of 40 human and 19 veterinary drug store pharmacists were interviewed in Nairobi in 2018 using a standard questionnaire. Data recorded included demographic variables, types of antibiotics sold, antibiotic customers, antibiotic prescribing practices and knowledge of antibiotic use and AMR.

resultsOur study shows that at the retail level, there is a considerable overlap between antibiotic classes (10/15) sold for use in both human and veterinary medicine. Whilst in our study, clinical training significantly influenced knowledge on issues related to antibiotic use and AMR and respondents had a relatively adequate level of knowledge about AMR, several inappropriate prescribing practices were identified. For example, we found that most veterinary and human drug stores (100% and 52% respectively) sold antibiotics without a prescription and noted that customer preference was an important factor when prescribing antibiotics in half of the drug stores.

conclusionAlthough more research is needed to understand the drivers of antibiotic consumption in both human and animal populations, these findings highlight the need for immediate strategies to improve prescribing practices across the pharmacists in Nairobi and by extension other low- and middle-income country settings.

Indexed as

Health Knowledge, Attitudes, PracticeAdultAnimalsAnti-Bacterial AgentsCross-Sectional StudiesDrug Resistance, MicrobialFemaleHumansInappropriate PrescribingKenyaMalePharmacistsSurveys and QuestionnairesAnti-Bacterial Agents

Identifiers

PMID31489183
PMCPMC6708591
OpenAlexW2969851167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.