ArticleChemical science2019
Formamide catalyzed activation of carboxylic acids - versatile and cost-efficient amidation and esterification.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Solvent Sustainability in Drug Discovery: Where Are We Now, and How Can We Improve?Journal of medicinal chemistry · 2025Review
- Biomimetic Carbon-Based Nanomaterials: From Design Strategies to Next-Generation Biosensing and Theranostic Applications.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Direct conversion of various phosphate sources to a versatile P-X reagent [TBA][PONature communications · 2025Article
- Recent advances in synthetic approaches for bioactive cinnamic acid derivatives.Beilstein journal of organic chemistry · 2025Review
- A sustainable, efficient, and potentially cost-effective approach to the antimalarial drug candidate MMV688533.Chemical science · 2023Article
- Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green.Chemical science · 2023Article
- Innovative application of magnetically modified bovine horn as a natural keratin resource in the role of value-added organocatalyst.RSC advances · 2022Article
- Catalytic and non-catalytic amidation of carboxylic acid substrates.Molecular diversity · 2022Review
- Rapid Organocatalytic Formation of Carbon Monoxide: Application towards Carbonylative Cross Couplings.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Ultrafast amidation of esters using lithium amides under aerobic ambient temperature conditions in sustainable solvents.Chemical science · 2020Article
- Synthesis and Characterization of New Series of 1,3-5-Triazine Hydrazone Derivatives with Promising Antiproliferative Activity.Molecules (Basel, Switzerland) · 2020Article
- Deoxygenative trifluoromethylthiolation of carboxylic acids.Chemical science · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel, broadly applicable method for amide C-N and ester C-O bond formation is presented based on formylpyrrolidine (FPyr) as a Lewis base catalyst. Herein, trichlorotriazine (TCT), which is the most cost-efficient reagent for OH-group activation, was employed in amounts of ≤40 mol% with respect to the starting material (100 mol%). The new approach is distinguished by excellent cost-efficiency, waste-balance (
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.