Evidence map›Paper›PMID 31489157›Full record

ArticleChemical science2019

Stereoselective total synthesis of parthenolides indicates target selectivity for tubulin carboxypeptidase activity.

Robert R A Freund, Philipp Gobrecht, Zhigang Rao, Jana Gerstmeier, Robin Schlosser, Helmar Görls, Oliver Werz, Dietmar Fischer, Hans-Dieter Arndt

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Targeting Vasohibins to Promote Axon Regeneration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  4. Chalcone: A potential scaffold for NLRP3 inflammasome inhibitors.European journal of medicinal chemistry reports · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Robert R A FreundInstitut für Organische Chemie und Makromolekulare Chemie , Friedrich-Schiller-Universität , Humboldtstr. 10 , 07743 Jena , Germany . Email: hd.arndt@uni-jena.de.ORCID 0000-0001-5771-3237
Philipp GobrechtLehrstuhl für Zellphysiologie , Ruhr-Universität Bochum , Universitätsstr. 150, ND/4 , 44780 Bochum , Germany.
Zhigang RaoInstitut für Pharmazie , Friedrich-Schiller-Universität , Philosophenweg 14 , 07743 Jena , Germany.
Jana GerstmeierInstitut für Pharmazie , Friedrich-Schiller-Universität , Philosophenweg 14 , 07743 Jena , Germany.
Robin SchlosserInstitut für Organische Chemie und Makromolekulare Chemie , Friedrich-Schiller-Universität , Humboldtstr. 10 , 07743 Jena , Germany . Email: hd.arndt@uni-jena.de.
Helmar GörlsInstitut für Anorganische Chemie und Analytische Chemie , Friedrich-Schiller-Universität , Humboldtstr. 8 , 07743 Jena , Germany.
Oliver WerzInstitut für Pharmazie , Friedrich-Schiller-Universität , Philosophenweg 14 , 07743 Jena , Germany.
Dietmar FischerLehrstuhl für Zellphysiologie , Ruhr-Universität Bochum , Universitätsstr. 150, ND/4 , 44780 Bochum , Germany.ORCID 0000-0002-1816-3014
Hans-Dieter ArndtInstitut für Organische Chemie und Makromolekulare Chemie , Friedrich-Schiller-Universität , Humboldtstr. 10 , 07743 Jena , Germany . Email: hd.arndt@uni-jena.de.ORCID 0000-0002-0792-1422

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2-(silyloxymethyl)allylboration of aldehydes was established to enable stereoselective access to α-(

Identifiers

PMID31489157
PMCPMC6713873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.